Standard Manual Aneroid Sphygmomanometer for Aneurysm

1
Effectiveness
1
Safety
Jackson Memorial Hospital, Miami, FL
Aneurysm+2 More
Standard Manual Aneroid Sphygmomanometer - Device
Eligibility
18+
All Sexes
Eligible conditions
Aneurysm

Study Summary

This study is evaluating whether a procedure which reduces bloodflow in a limb may help protect the brain from low blood flow.

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Eligible Conditions

  • Aneurysm
  • Berry Aneurysm
  • Intracranial Aneurysm
  • Unruptured Cerebral Aneurysm

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Standard Manual Aneroid Sphygmomanometer will improve 1 primary outcome and 4 secondary outcomes in patients with Aneurysm. Measurement will happen over the course of 2-4 days post procedures..

2-4 days post procedures.
Frequency of large (>10 cc value) strokes.
9 months
Incidence of all adverse events and serious adverse events.
Baseline, 3-9 months.
Change in procedurally-induced vascular cognitive impairment.
Hour 96
Volume of embolic strokes by Diffusion Weighted Imaging (DWI).
Hour 96
Volume of embolic strokes by Fluid-attenuated Inversion Recovery (FLAIR).

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Sham group: standard blood pressure cuff
Treatment group: standard blood pressure cuff
Placebo group

This trial requires 50 total participants across 2 different treatment groups

This trial involves 2 different treatments. Standard Manual Aneroid Sphygmomanometer is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.

Treatment group: standard blood pressure cuff
Device
A standard blood pressure cuff inflated on the participants arm for 4 cycles; each cycle will include 5 minutes of inflation followed by 5 minutes of deflection. RIPC will be applied via a standard blood pressure cuff. The ischemic cycle will involve cuff inflating to 30mmHg above resting systolic blood pressure and demonstration of loss of radial pulse.
Sham group: standard blood pressure cuff
Device
The blood pressure cuff will be inflated to 30mmHg during the first 5 minutes of each cycle and deflated for the following 5 minutes, with re-demonstration of radial pulse. This will be repeated for 4 cycles.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 3-9 months.
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline, 3-9 months. for reporting.

Closest Location

Jackson Memorial Hospital - Miami, FL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Subjects who have not had any symptoms of a stroke, such as transient ischemic attacks (TIAs), minor strokes, stroke-in-evolution, or clinical evidence of cerebral vasospasm, within the two weeks prior to randomization are eligible for the study show original
The subject consents to taking part in the study and is available for the entire study period show original
Any person who is male or female and is at least 18 years old on the day of enrollment is eligible to participate. show original
A patient with an unruptured brain aneurysm may be a candidate for repair by neuroendovascular techniques involving intraluminal occlusion by detachable platinum coils, stent-assisted coiling, pipeline stent, balloon-assisted coiling, covered stent only, neck-bridge device, re-coiling, or re-treatment of a previously coiled/treated aneurysm show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes aneurysm?

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The causes of aneurysmal disease are not clear and it is possible that its development is influenced by other diseases. The main risk factors for developing an aneurysm are smoking and older age. Other factors such as genetics, familial aggregation and high blood pressure may also contribute to the aetiology of aneurysmal disease.

Unverified Answer

What are common treatments for aneurysm?

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If a treatment for an aneurysm has not been reported by a researcher on that subject, and if one is not listed in the [Appendix of the end] <nowiki>[end of the reference list]</nowiki>, then I suggest that a research group should first [contact]] and ask permission to use the material in their manuscript. Once permission is acknowledged, the research group should [contact]] and obtain appropriate informed consent before the study can be performed. The consent process is [important since the studies that employ patient material have] more than reasonable concern for the rights and welfare of those patients.

Unverified Answer

What is aneurysm?

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An aneurysm is a dilated, and sometimes partially or completely ruptured, hollow or over-filled space within a major vessel, which may be the thoracic, abdominal, or a peripheral artery, or the branch of such vessel. The commonest site of aneurysms is the thoracic aorta. Aortic aneurysms and dissections (thoracic and abdominal) account for a substantial percentage of aortic deaths. Thus, aneurysms deserve an in depth perspective.

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Can aneurysm be cured?

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This single-center, retrospective study of 11 patients does not show evidence that aneurysm can be cured. However, it does show that aneurysm can be cured to a degree and that complete obliteration does not guarantee complete cure.

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What are the signs of aneurysm?

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An aneurysm is a medical diagnosis and has signs and symptoms depending on its size and location. In most cases, these are not serious, but complications can follow an expansion of the aneurysm in the brain or inside the aorta. The signs and symptoms depend on the size of the aneurysm.\n

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How many people get aneurysm a year in the United States?

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About 4% of people developed an aneurysm during the period 1996 to 2006 in the United States, a rate that has increased substantially during this period, although the proportion of women with AAA was lower than among men. Since this may be partially obscured by underreporting of cases due to the rarity of symptomatic presentation of AAA, a more realizable figure of 5 to 8 cases per 100,000 would be appropriate. Because patients with rheumatoid arthritis and other autoimmune disorders have 2-fold increased risk of AAA, they could be at higher risk for AAA than the general population. Patients with familial aortic aneurysms or dissections may be at an even higher risk.

Unverified Answer

What does standard manual aneroid sphygmomanometer usually treat?

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We have shown that using a hand-held sphygmomanometer could reduce the number of arterial hemorrhages when compared to standard manual sphygmomanometer for patients with subclavian or femoral arterial aneurysm.

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Does standard manual aneroid sphygmomanometer improve quality of life for those with aneurysm?

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The inclusion of an aneroid sphygmomanometer in the clinic improves the quality of life of those with an aneurysm, as demonstrated by both their decreased use of the medical facility and their self-diagnosis of hypo- or hypertension.

Unverified Answer

What is the average age someone gets aneurysm?

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The average age someone gets an aneurysm in Finland varies based on the type of aneurysm. Visceral aneurysms have been found earlier on average compared to cerebral aneurysms (46 vs 45 yr, respectively). This difference might be due to the earlier use of invasive cardiovascular imaging during examination of people with abdominal pain and signs of aneurysm.

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What are the latest developments in standard manual aneroid sphygmomanometer for therapeutic use?

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The most innovative feature of the newest manual aneroid sphygmomanometers is the increased ease of operation (by reducing errors due to hand tremors) for the patients and their caregivers. There were no clear indications for using an electronic version. There were also shortcomings in terms of standardisation of construction and precision.

Unverified Answer

What is the latest research for aneurysm?

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Aneurysms occur in everyone but some are related to more than one risk factors, such as aging, smoking, gender, family history of aneurysms, and history of previous aneurysm. Furthermore, aneurysms can be treated. Physicians should check up aneurysms regularly and keep them under careful monitoring.

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What are the common side effects of standard manual aneroid sphygmomanometer?

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Data from a recent study has shown that the common side effects of MS are the main reasons for the abandonment of MS as a sphygmomanometer. However, it is clear that MS is not the only alternative. Although the MS is not preferable because of its unique properties, it can still be recommended for clinical use. If the MS is indicated, other sphygmomanometers should be considered.

Unverified Answer
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