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Ischemic Preconditioning for Ischemic Preconditioning

N/A

Waitlist Available

Research Sponsored by Medical College of Wisconsin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up admission into study and within 3 days of discharge from froedtert hospital

Awards & highlights

Study Summary

This trial will use ischemic preconditioning to try and improve stroke rehabilitation. IPC is an intervention which has been shown to improve regional blood flow, motor neuron excitability and muscle function. Because IPC targets three physiological systems which are all affected by stroke, the hypothesis is that repeated bouts of IPC during the first days to months following stroke will make traditional rehabilitation strategies more effective.

Eligible Conditions

Ischemic Preconditioning
Stroke Rehabilitation
Physical and Rehabilitation Medicine

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ admission into study and within 3 days of discharge from froedtert hospital

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~admission into study and within 3 days of discharge from froedtert hospital

This trial's timeline: 3 weeks for screening, Varies for treatment, and admission into study and within 3 days of discharge from froedtert hospital for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Knee Extensor Strength

Secondary outcome measures

Change in Walking Speed

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Ischemic PreconditioningExperimental Treatment1 Intervention

Inflation of blood pressure cuff to 225 mmHg on paretic leg. 1 session: 5 minutes of inflation, 5 minutes deflation, repeated 5 times.

Group II: ShamPlacebo Group1 Intervention

Inflation of blood pressure cuff to 25 mmHg on paretic leg. 1 session: 5 minutes of inflation, 5 minutes deflation, repeated 5 times.

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Who is running the clinical trial?

Medical College of WisconsinLead Sponsor

609 Previous Clinical Trials

1,162,581 Total Patients Enrolled

Marquette UniversityOTHER

62 Previous Clinical Trials

200,303 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it feasible for participants to join this experiment at the present?

"Clinicaltrials.gov records indicate that this trial is not actively searching for participants at present, with the initial post date of October 1st 2016 and its last edit on October 14th 2021. However, there are over a thousand other studies recruiting patients right now."

Answered by AI

Are individuals below the age of twenty-five eligible to participate in this experiment?

"Patients hoping to join this research must be between 40 and 80 years of age. There are 68 trials for those below the legal minimum, with 1217 studies available for seniors beyond 65."

Answered by AI

Is it feasible to participate in the trial?

"This medical experiment is recruiting 50 individuals aged between 40 and 80 who are in the process of stroke rehabilitation. As a condition for participation, candidates must be < 6 months post diagnosis of unilateral cortical stroke, have residual leg paresis, as well as provide informed consent."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Ischemic Preconditioning as an Intervention to Improve Stroke Rehabilitation - Froedtert

Matthew J. Durand 2016. "Ischemic Preconditioning as an Intervention to Improve Stroke Rehabilitation - Froedtert". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03023150.