Static Magnetic Fields for Peripheral Vascular Disease

Overseen By Harvey Mayrovitz

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Nova Southeastern University

Disqualifiers: Diabetes, Metallic implant, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: 1 hour

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how small magnets might affect blood flow and pulse in the skin. Researchers aim to determine if static magnetic fields impact circulation. The trial includes two groups: one using a real magnet and the other using a sham (fake) magnet for comparison. Ideal participants are healthy adults without neurological or cardiovascular issues who can remain still for about an hour. As an unphased trial, this study allows participants to contribute to pioneering research on magnetic effects on circulation.

Do I need to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this method is safe for peripheral vascular disease?

Research has shown that static magnetic fields (SMFs) are generally safe for people. A review of 56 studies found no major safety concerns, including both patients and healthy volunteers. One study found that short exposure to SMFs did not affect pain or heart function. Some reports suggest SMFs might improve blood flow by widening blood vessels. Overall, the treatment appears safe, but further research is needed to confirm these findings. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Unlike standard treatments for peripheral vascular disease, which often involve medications, lifestyle changes, or surgical interventions, the use of static magnetic fields offers a completely different approach. Researchers are intrigued by this method because it involves applying magnets to potentially improve blood circulation without the need for drugs or invasive procedures. This non-invasive technique could offer a safer and more convenient option for patients, potentially reducing side effects and enhancing quality of life.

What evidence suggests that static magnetic fields are effective for peripheral vascular disease?

This trial will compare the effects of static magnetic fields (SMF) using magnets with a sham treatment in healthy adults. Research has shown mixed results for using SMF to improve blood flow. Some studies did not find any increase in blood flow, and one even showed a decrease. However, SMF shows promise in other areas. For instance, it has helped reduce pain for people with diabetic nerve damage. Another study suggested a slight decrease in leg pain for people with chronic sciatica using magnets, though the change wasn't significant. Overall, while some evidence suggests SMF can aid in pain relief, its effects on blood flow remain uncertain based on current research. ^{1 3 6 7 8}

Are You a Good Fit for This Trial?

This trial is for young adults aged 18-35 with no neurological or cardiovascular conditions. It's not suitable for those who can't stay still for almost an hour, diabetics, or individuals with metal/wire implants.

Inclusion Criteria

I do not have any known heart conditions.

I do not have any known nerve or brain problems.

Exclusion Criteria

I cannot or do not want to stay still for about 55 minutes.

I have been diagnosed with diabetes.

You have any metal or wire implants in your body.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants are exposed to static magnetic fields and sham devices to assess effects on peripheral pulses and skin blood flow

1 hour

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1-2 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Magnet
• Sham

Trial Overview The study is examining the effects of a small magnet (static magnetic fields) on peripheral pulses and skin blood flow compared to a sham (inactive) treatment.

How Is the Trial Designed?

Group I: Healthy Adults-magnet Experimental Treatment 1 Intervention

Healthy adults with magnet and/or sham

Group II: Healthy Adults-sham Placebo Group 1 Intervention

Healthy adults with magnet and/or sham

Who Is Running the Clinical Trial?

Nova Southeastern University

Lead Sponsor

Trials

103

Recruited

12,000+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC2686626/

Static Magnetic Field Therapy: A Critical Review of ... Despite the lack of scientific recommendations for SMF dosage and treatment regimens, multiple clinical trials have been conducted to evaluate SMF efficacy.

2. withpower.com withpower.com/trial/phase-peripheral-vascular-diseases-8-2021-3ca2d

Static Magnetic Fields for Peripheral Vascular Disease The purpose of this research study is to investigate and determine the effects of static magnetic fields produced by a small magnet on peripheral pulses and ...

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11859515/

Investigations Into the Impact of Static Magnetic Fields on ... With regard to human studies, none showed an increase in blood flow, and one showed a decrease in flow. With regard to the animal studies, one ...

4. dmsjournal.biomedcentral.com dmsjournal.biomedcentral.com/articles/10.1186/s13098-023-01123-9

Effect of static magnetic field therapy on diabetic neuropathy ... The results suggest that the magnetic device was effective in reducing pain severity in participants with a range of pain severity levels, ...

5. sciencedirect.com sciencedirect.com/science/article/pii/S0885392407003338

Low Intensity Permanent Magnets in the Treatment of ... This randomized, controlled, double-blind study showed a nonsignificant trend toward leg pain reduction in patients with chronic sciatica exposed to magnets of ...

6. clinicaltrials.gov clinicaltrials.gov/study/NCT04539704?term=%22nova+southeastern+university%22

Assessing Impacts of Static Magnetic Fields on Peripheral ... An unfavorable change in the health of a participant, including abnormal laboratory findings, that happens during a clinical study or within a certain amount of ...

7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC9184174/

Do Magnetic Fields Have a Place in Treating Vascular ... Static magnetic fields (SMFs) have been reported to increase microcirculatory blood flow by mediating vasodilation via nitric oxide.

8. journals.physiology.org journals.physiology.org/doi/full/10.1152/japplphysiol.00734.2006

Influence of static magnetic fields on pain perception and ... These results indicate that acute exposure to static magnetic fields does not alter pain perception, sympathetic function, and hemodynamics at rest or during ...