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Ibuprofen for Distal Radius Fracture (Adult NSAID Trial)
Adult NSAID Trial Summary
This trial is testing whether or not non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are just as effective as acetaminophen at reducing pain and the use of opioids after carpal tunnel surgery.
- Distal Radius Fracture
Adult NSAID Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Adult NSAID Trial Design
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- You cannot take non-steroidal anti-inflammatory drugs (NSAIDs) because of a condition like stomach ulcers, kidney disease, or bleeding disorders.You have multiple injuries, including orthopaedic injuries.You cannot take other medications if needed during the study.You take strong pain medication on a regular basis.You have a bone fracture where the bone has broken through the skin.You have a broken bone caused by a disease or condition.You take non-steroidal anti-inflammatory drugs (NSAIDs) on a regular basis.You have had a previous bone injury.You have a broken wrist bone called the distal radius.You are currently pregnant or planning to become pregnant.
- Group 1: Operative NSAID
- Group 2: Non-operative Acetaminophen
- Group 3: Non-operative NSAID
- Group 4: Operative Acetaminophen
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What conditions can be alleviated by taking Ibuprofen?
"Ibuprofen is usually prescribed to alleviate catarrh and it has also been proven effective at treating several other conditions, including rhinorrhoea, musculoskeletal discomfort, and muscle spasms."
Does Ibuprofen present any significant health risks for individuals?
"There is substantial clinical evidence in support of Ibuprofen's safety, and as a result, it was given an assessment of 3."
How many participants have joined this medical research?
"Affirmative. Clinicaltrials.gov has documented that this clinical trial is actively recruiting volunteers, and was initially posted on January 2nd 2019 with its most recent update occurring November 22nd 2021. A total of 200 patients are needed for the single location hosting this study."
What other investigations have been undertaken concerning Ibuprofen?
"At present, 108 trials are actively studying Ibuprofen with 32 of these in the final phase before approval. Pittsburgh serves as the hub for this research, but there exists a network of 1032 sites across the world that house clinical investigations into ibuprofen's efficacy."
Are there any current opportunities to enroll in this research endeavor?
"Affirmative. Records hosted on clinicaltrials.gov indicate that this research is currently seeking volunteers, with a listing posted as of February 1st 2019 and most recently updated November 22nd 2021. The trial requires 200 participants from one site to be recruited in total."
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