NSAID capsules for Osteoarthritis of the Thumb

Phase-Based Progress Estimates
Stanford Health Care, Redwood City, CAOsteoarthritis of the Thumb+1 MoreNSAID capsules - Drug
All Sexes
What conditions do you have?

Study Summary

This trial found that a combination of over the counter NSAIDs was as effective as the prescription opioid oxycodone for pain management in the first month after surgery for thumb osteoarthritis.

Eligible Conditions
  • Osteoarthritis of the Thumb
  • Postoperative Pain

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

4 Primary · 2 Secondary · Reporting Duration: Baseline, Post-operative weeks 1, 3, 5, and 8

Week 1
Change in PROMIS-PI scores over time
Change in Quick DASH scores over time
Day 30
Pharmaceutical Preparations
Change of worst daily pain score measured over time

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

1 of 2
1 of 2

Experimental Treatment

121 Total Participants · 2 Treatment Groups

Primary Treatment: NSAID capsules · No Placebo Group · Phase 2

Experimental Group · 1 Intervention: Opioid capsule · Intervention Types: Drug
Experimental Group · 1 Intervention: NSAID capsules · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, post-operative weeks 1, 3, 5, and 8

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,182 Previous Clinical Trials
35,790,632 Total Patients Enrolled
Amy Ladd, MDPrincipal InvestigatorStanford Orthopaedic Surgery

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are having surgery to treat osteoarthritis in your thumb called trapeziectomy.

Frequently Asked Questions

To what extent are NSAID capsules a hazard for people seeking treatment?

"Although no efficacy data has been gathered, there are safety studies in place for NSAID capsules. Therefore, the assessment of its safety received a rating of 2 out of 3." - Anonymous Online Contributor

Unverified Answer

Are there available slots in this experiment for participants?

"According to the data hosted on clinicaltrials.gov, enrollment is still open and this trial has been actively recruiting since its inception on December 27th 2021. The most recent update was also posted on that same day." - Anonymous Online Contributor

Unverified Answer

What is the size of this medical research project's cohort?

"Affirmative. According to clinicaltrials.gov, this medical trial has been actively recruiting since December 27th 2021 and just recently underwent its last update on the same day. The study is seeking 121 patients from 1 site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.