This trial is evaluating whether Ibuprofen will improve 1 primary outcome and 4 secondary outcomes in patients with Fractures, Bone. Measurement will happen over the course of Between 3 months and 12 months after definitive fixation surgery.
This trial requires 1000 total participants across 2 different treatment groups
This trial involves 2 different treatments. Ibuprofen is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 3 and have had some early promising results.
"There are two treatments to heal segond fractures in adults, according to some professional, including nonoperative treatment and conservative treatment with traction and cast casting which is only used in children. The treatment depended on the healing condition of the bone. Nonoperative treatment and conservative treatment with traction and cast casting are used in both children and adults. These treatments make good therapeutic goals for segond fractures." - Anonymous Online Contributor
"The fractures related to the lower extremities and proximal femur as a result of fall probably account for the majority of segond fractures in our population." - Anonymous Online Contributor
"The segond fracture is a very rare injuries with an overall mortality of 3.0%. We cannot definitively state that the segond fracture can be a curatable injury. However, patients can live a normal life and return to their daily activities after the fractures. This is because the segond fracture can be treated conservatively and, in most cases, does not need a surgical fixation as most of the time the fracture heals itself. The use of surgical screws is suggested for those patients who have a fracture that appears to require a fixation technique that includes the possibility of removing and re-implanting the screw, which may be a solution for selected patients with segond fractures." - Anonymous Online Contributor
"About 26,000 people per year have hip fractures, or 12,000 per year who have upper-extremity fractures. About 14,000 people per year have lower-extremity fractures, 9,500 per year who have a neck fracture, and 8,000 per year who have a trochanteric fracture. Nearly 30% of segond-fractured people die within 1 year of their injury." - Anonymous Online Contributor
"Trauma of the skull base can result in pain, discharge, tearing, and numbness below the level of the eye muscle. On the side of the eye with a fracture, there are symptoms of the eye socket fracture and in particular, iritis that often occurs within the first day after the injury.\nThis article is protected by copyright. All rights reserved." - Anonymous Online Contributor
"Segond fractures are a fracture of the long (third) metacarpal bone that is often associated with arthritis and a previous injury to the same hand. In 90% of cases, a history of a previous injury to the same hand may be present. Patients who suffer a segond fracture often complain of pain in the same wrist(s) that is aggravated by pushing into a hard surface. If pain is not responding to analgesics (pain pills), and the patient is willing to try oral analgesics, then it's time to seek urgent medical attention by a qualified health practitioner. The prognosis for segond fractures is excellent in the presence of prompt medical attention." - Anonymous Online Contributor
"Ibuprofen (400 mg twice daily for 2-4 doses is usually recommended as a treatment for children with fever-temperamental fractures or children with mild [knee pain](https://www.withpower.com/clinical-trials/knee-pain) due to osteochondrosis. Ibuprofen is inexpensive compared with other analgesics, is readily available, and is usually effective in treating mild and moderate pain/fracture pain. Although ibuprofen is effective, it does not heal the broken bone at a quick pace. In order to treat more aggressive injuries, such as severe knee pain with more serious bone broken, a child will be referred for surgery that requires anesthetics and intravenous lines and many other specialized services." - Anonymous Online Contributor
"There's a lot of research on how to treat segond fracture, and we're just discovering how much more complicated this disease is than we thought earlier. Some things we found that helped us were: good nutrition, stopping bad habits, and seeing the doctor for help. We think that these will help the rest of the world to get better treatments for SEGOND fracture too." - Anonymous Online Contributor
"Pain medication remains a useful adjunct to surgical fixation of fractures, both in the acute hospital setting and in the community. In the acute setting, ibuprofen does not preclude an operative programme, and so should be allowed before other analgesics or opioid-based medications are administered. Ibuprofen can be regarded as a first line alternative to paracetamol. The use of ibuprofen and paracetamol in the treatment of moderate to severe [knee pain](https://www.withpower.com/clinical-trials/knee-pain) and hip pain is a very common practice and evidence does not support its safety." - Anonymous Online Contributor
"Ibuprofen is generally associated with pain at the injection site and gastrointestinal effects (mainly dyspepsia, indigestion and diarrhea), and less commonly with allergic reactions. However, a wide diversity of adverse effects was noted, and no clear patterns were identified." - Anonymous Online Contributor
"The most common cause of segond fractures in our institution and in a series of previously published studies was osteoporosis. Other common causes of segond fractures were osteomalacia, post-partum blues, and fractures due to trauma. Bone mineral density screening will help to identify patients who are at risk of developing segond fractures." - Anonymous Online Contributor