Pain Management for Trauma Recovery
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will attempt to determine if there is a statistic difference between the time to union, non-union rate and post-operative pain of patients who receive opioids for pain control vs. patients who receive NSAIDs and a reduced dosage of opioids for pain management
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Are NSAIDs generally safe for humans?
NSAIDs (nonsteroidal anti-inflammatory drugs) are commonly used for pain relief but can cause serious side effects like stomach ulcers, heart issues, and kidney problems, especially at high doses or with long-term use. To minimize risks, it's recommended to use the lowest effective dose for the shortest time possible and consider additional protective measures if you have risk factors.12345
How do NSAIDs differ from other drugs for trauma pain management?
NSAIDs (nonsteroidal anti-inflammatory drugs) are unique in trauma pain management because they can reduce the need for opioids, which are often associated with side effects like respiratory depression and nausea. Unlike opioids, NSAIDs do not cause these side effects, potentially allowing for faster recovery and earlier discharge from medical care.678910
What data supports the effectiveness of the drug NSAIDs for pain management in trauma recovery?
Who Is on the Research Team?
Rodolfo Zamora, MD
Principal Investigator
University of Louisville
Are You a Good Fit for This Trial?
This trial is for individuals aged 18 to 105 who have a specific type of tibia fracture (OTA/AO 42 A, B) and are receiving intramedullary nails as treatment. Those with different types of tibial fractures not treated this way cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either NSAIDs with reduced opioids or standard opioids for pain control post-operatively
Follow-up
Participants are monitored for time to union, non-union rate, and post-operative pain using a VAS pain scale
What Are the Treatments Tested in This Trial?
Interventions
- NSAIDs
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Louisville
Lead Sponsor