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Central Nervous System Stimulant

A for Attention Deficit Hyperactivity Disorder (ADHD)

Phase 4
Waitlist Available
Led By Mona Ismail, MD
Research Sponsored by BRC Operations Pty. Ltd.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 52 weeks
Awards & highlights

Study Summary

The aim of the iSPOT-A study is to: identify brain, genetic and cognitive markers of Attention Deficit/Hyperactivity Disorder, and identify brain, genetic and cognitive markers that predict treatment response to short-acting methylphenidate in children and adolescents diagnosed with Attention Deficit/Hyperactivity Disorder.

Eligible Conditions
  • Attention Deficit Hyperactivity Disorder (ADHD)

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~52 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 52 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
To determine whether the genetic-brain-cognition function markers (or combination of markers) 'normalize' with acute drug treatment in ADHD.
Secondary outcome measures
To determine whether markers of acute treatment prediction are also predictive of functional outcome over 6-12 months.

Trial Design

3Treatment groups
Active Control
Group I: AActive Control1 Intervention
Short Acting methylphenidate
Group II: BActive Control1 Intervention
Long Acting Methylphenidate
Group III: CActive Control1 Intervention
Healthy Controls

Find a Location

Who is running the clinical trial?

BRC Operations Pty. Ltd.Lead Sponsor
1 Previous Clinical Trials
2,688 Total Patients Enrolled
Mona Ismail, MDPrincipal InvestigatorBrain Resource Center NJ
1 Previous Clinical Trials
2,688 Total Patients Enrolled
Simon Clarke, MDPrincipal InvestigatorBrain Dynamics Centre

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
International Study to Predict Optimised Treatment in Attention Deficit/Hyperactivity Disorder
2009. "International Study to Predict Optimised Treatment in Attention Deficit/Hyperactivity Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00863499.
All > Obsessive Compulsive Disorder
~86 spots leftby May 2025
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