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Platelet-rich Plasma

PRP for Eyebrow Hypotrichosis and Alopecia Areata

Phase 2

Recruiting

Led By Murad Alam

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to 6 months

Awards & highlights

Study Summary

This trial is to test whether autologous platelet-rich plasma can help treat eyebrow hypotrichosis, or insufficient eyebrow hair growth. 40 people will be randomly chosen to either receive the plasma injections or a placebo saline solution. The trial will last 9 months.

Who is the study for?

This trial is for adults aged 18-85 in the Chicago area with mild to moderate eyebrow thinning who are healthy and can give informed consent. It's not for those with uncontrolled diseases affecting hair growth, recent use of certain hair growth drugs, significant blood disorders, genetic conditions impacting fibroblasts or collagen, pregnant/breastfeeding individuals, or those unable to follow the study protocol.Check my eligibility

What is being tested?

The trial tests if injections of platelet-rich plasma (PRP) help people with sparse eyebrows compared to saline (saltwater) injections. About 40 participants will be randomly chosen to receive either PRP or saline over a period of nine months in this pilot study aimed at assessing procedure feasibility.See study design

What are the potential side effects?

While specific side effects aren't listed here, common ones from similar procedures may include discomfort at injection sites, infection risk, bruising or bleeding especially in those with clotting disorders. The safety profile will be closely monitored throughout the study.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Clinical change of eyebrow hypotrichosis, as determined by scoring photographs

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Platelet-Rich PlasmaExperimental Treatment1 Intervention

Participants will receive intradermal injections of 2-3mL autologous PRP to eyebrows.Three treatments will be performed 1 month apart.

Group II: Placebo (sterile saline)Placebo Group1 Intervention

Participants will receive intradermal injections of 2-3mL sterile saline to eyebrows.Three treatments will be performed 1 month apart.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor

1,589 Previous Clinical Trials

917,096 Total Patients Enrolled

Murad AlamPrincipal Investigator - Northwestern University

Northwestern Memorial Hospital

Yale University School Of Medicine (Medical School)

Ny And Presby Hospital (Residency)

Media Library

Platelet-rich Plasma (Platelet-rich Plasma) Clinical Trial Eligibility Overview. Trial Name: NCT04018859 — Phase 2

Eyebrow Hypotrichosis Research Study Groups: Placebo (sterile saline), Platelet-Rich Plasma

Eyebrow Hypotrichosis Clinical Trial 2023: Platelet-rich Plasma Highlights & Side Effects. Trial Name: NCT04018859 — Phase 2

Platelet-rich Plasma (Platelet-rich Plasma) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04018859 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to take part in this research?

"Up to 30 individuals with hypotrichosis will be included in this study. The subject must meet the following requirements: They must of age (18-85), male or female, and have a clean bill of health."

Answered by AI

Are geriatric patients welcome in this clinical trial?

"According to the study's rules for who can participate, the youngest person that could be enrolled is 18 years old and the oldest patient that can take part in the trial is 85."

Answered by AI

How many test subjects are involved in this research?

"That is correct. The clinical trial was first posted on 9/25/2019 and was most recently updated on 12/22/2021, as indicated by the data available on clinicaltrials.gov. This study is looking for 30 patients between 1 sites."

Answered by AI

Are patients currently being recruited for this research study?

"From what is stated on clinicaltrials.gov, this particular trial is still in need of participants. The first posting was on September 25th, 2019 with the most recent update being December 22nd, 2021."

Answered by AI

Does the FDA allow for Platelet Rich Plasma Prep System to be used on patients?

"As this is a Phase 2 trial, there is some data indicating that Platelet Rich Plasma Prep System is safe. However, as there has not been any research done yet to support its efficacy, it received a score of 2."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Platelet-rich Plasma for Eyebrows

Murad Alam 2019. "Platelet-rich Plasma for Eyebrows". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04018859.

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