This trial is evaluating whether Platelet Rich Plasma Prep System will improve 1 primary outcome in patients with Hypotrichosis. Measurement will happen over the course of Baseline to 6 months.
This trial requires 30 total participants across 2 different treatment groups
This trial involves 2 different treatments. Platelet Rich Plasma Prep System is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 2 and have already been tested with other people.
"There is a wide spectrum of cutis dyschromia conditions, ranging from aplastic alopecia and congenital leukodermia to acquired hypopigmentation disorders. It is important to consider cutis dyschromia conditions in the differential diagnosis of alopecia-associated or systemic disease." - Anonymous Online Contributor
"Because many skin and hair problems can cause hypopigmentation, it is essential for health-care professionals to consider other causes of the patient's hair loss, especially if the skin does not appear to have any abnormalities, and can not be easily explained by the aforementioned causes." - Anonymous Online Contributor
"Hypotrichosis and hair loss are not treatable. They require no treatment. One should look at the skin for the first sign of alopecia, which could indicate a more serious condition." - Anonymous Online Contributor
"There were 2.7 million new cases of hypotrichosis in the study population with 6,730 deaths. The age standardised prevalence of hypotrichosis, at 8.2% per 1000 people, is far greater than previously reported from epidemiological studies. The high rate of new disease in this age-group warrants a high priority from the public health service." - Anonymous Online Contributor
"This condition causes the skin to appear shiny and wrinkled, with a rough texture. Thickening and tightening of hair (hirsutism) causes the hair to appear short and kinky, especially on the front. Reduced hair volume causes an increase in scalp hair, whereas hair on the back may get thinner. Decreased hair growth also creates thin hairs. Thickening, darkening and tightening may be caused by hormonal disturbances. Insufficient hair volume may lead to ingrowing eyebrows and ears. A weakened immune system may make hair fall out, especially in the neck and shoulders. Some women, who are not immunosuppressed, do develop thick hair to the mid-back." - Anonymous Online Contributor
"Hypotrichosis has many treatments. Depending on the severity of the condition, surgery, dermatology, and oral therapy are some of the treatments that have shown to have beneficial results in the past. The use of topical creams in this condition is relatively new and is still a controversial topic. However, further research is being performed to look into this and other possible treatments for this condition." - Anonymous Online Contributor
"This system can provide a high volume product to treat many diseases. This system can provide an effective and safe therapy, and it is a great improvement over the platelet PPP method." - Anonymous Online Contributor
"Platelet rich plasma is efficacious for hair growth and hair strength rejuvenation. The PRP with PRSP system is the first choice for the hair-growth therapy in patients with alopecia." - Anonymous Online Contributor
"The PRP system in the case of non-healing burn wounds has been used in various different clinical indications in which PRP injections/infusions are combined with other treatments such as a range of antiseptic and antibiologic preparations (wounded area and wounds to nails and skin area) which are used as treatment for chronic non-healing wounds. However, based on our results the use of PRP as a standalone treatment has been shown to be ineffective; this could explain why the use of PRP in the case of non-healing burns wound might be very useful for stimulating healing where PRP injections/infusions have been used with other treatments." - Anonymous Online Contributor
"Platelet rich plasma is a safe and effective modality for cutaneous soft tissue injuries and wounds in patients with grade III or I hypotrichosis. The method is economical, and results can be achieved faster and with better results than a placebos. Further research on the use of platelet rich plasma in patients with hypotrichosis is warranted." - Anonymous Online Contributor
"Parents of children with hypo- or hypertrichosis were much more likely to have hypo- or hypertrichosis themselves. Therefore, the hypothesis that hypo- and hypertrichosis is a hereditary condition seems to be valid. The reason for this is unknown." - Anonymous Online Contributor
"There are no contraindications to clinical trials of treatment for hypotrichosis that should be evaluated in the individual patient (a prospective clinical trial). However, considering the limitations of clinical studies, patients should be cautioned that there are many treatments to which they may be vulnerable." - Anonymous Online Contributor