Study Summary
This trial is testing whether combining testosterone gel with exercise can help hip fracture patients 65 and older heal better than exercise alone.
- Hip Fracture
- Frailty
- Frailty Syndrome
- Debilitated States
- Sarcopenia
- Preoperative Frailty
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 10 Secondary · Reporting Duration: Baseline and 6 months
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
2 Treatment Groups
Exercise + Testosterone (EX + T)
1 of 2
Exercise + Placebo (EX + P)
1 of 2
Experimental Treatment
Non-Treatment Group
129 Total Participants · 2 Treatment Groups
Primary Treatment: Testosterone · Has Placebo Group · Phase 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 65+ · Female Participants · 0 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Fairhall NJ, Dyer SM, Mak JC, Diong J, Kwok WS, Sherrington C. Interventions for improving mobility after hip fracture surgery in adults. Cochrane Database Syst Rev. 2022 Sep 7;9:CD001704. doi: 10.1002/14651858.CD001704.pub5. Review.
- Fairhall NJ, Dyer SM, Mak JC, Diong J, Kwok WS, Sherrington C. Interventions for improving mobility after hip fracture surgery in adults. Cochrane Database Syst Rev. 2022 Sep 7;9(9):CD001704. doi: 10.1002/14651858.CD001704.pub5.
- Ellen F. Binder, MD 2017. "Starting a Testosterone and Exercise Program After Hip Injury". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02938923.
Frequently Asked Questions
What does the FDA think of Supervised exercise training?
"Supervised exercise training has received a score of 3 from our team at Power. This is due to the fact that this is a Phase 3 trial, meaning there is some data supporting efficacy and multiple rounds of data supporting safety." - Anonymous Online Contributor
Are there any spaces available for new participants in this research?
"That is correct, the listed clinical trial on clinicaltrials.gov is recruiting patients. This specific research project was originally posted on September 15th, 2017 and has been updated as recently as May 31st, 2022. The study requires 120 individuals total at 6 different locations." - Anonymous Online Contributor
Where are patients able to participate in this trial?
"There are several places where patients can take part in this study, such as University of Connecticut Heath - UConn Health in Farmington, Connecticut; University of Pittsburgh Medical Center in Pittsburgh, Pennsylvania; or University of Utah in Salt Lake City, Utah." - Anonymous Online Contributor
What condition does Supervised exercise training help improve the most?
"Although often used to treat hypogonadotropic hypogonadism, supervised exercise training is a versatile therapy that can be taken to address a variety of other issues like 1 to 5 years post-menopausal, orchidectomy, orchitis." - Anonymous Online Contributor
Does this research paper's findings corroborate previous work on Supervised exercise training?
"As of right now, there are a total of 32 different clinical trials underway that are investigating the efficacy of Supervised Exercise Training. 5 of those trials are currently in Phase 3. The majority of studies for Supervised Exercise Training are based in Houston, Texas; however, there are a total of 158 locations across the globe running trials for this treatment." - Anonymous Online Contributor
How many test subjects are included in this experiment?
"In total, this study needs 120 individuals that match the pre-determined inclusion criteria. There are multiple locations where patients can take part in the trial, such as University of Connecticut Heath - UConn Health in Farmington, Connecticut and University of Pittsburgh Medical Center in Pittsburgh, Pennsylvania." - Anonymous Online Contributor