Thermography for Radiodermatitis

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Sunnybrook Hospital, Toronto, Canada
Radiodermatitis+1 More
Thermography - DiagnosticTest
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

Thermal Imaging to Evaluate Skin Toxicity From Radiotherapy

See full description

Eligible Conditions

  • Radiodermatitis
  • Radiotherapy Side Effects

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Thermography will improve 1 primary outcome and 1 secondary outcome in patients with Radiodermatitis. Measurement will happen over the course of 1 year.

1 year
Measure patient-reported toxicity using a validated self-assessment tool (Dermatology Quality of Life Questionnaire)
Temperature changes in skin during radiotherapy.

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Thermal Imaging
1 of 1
Experimental Treatment

This trial requires 200 total participants across 1 different treatment group

This trial involves a single treatment. Thermography is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Thermal Imaging
DiagnosticTest
Patients will undergo non-invasive, thermal imaging of their whole breast or head and neck cancer site, during the course of the radiotherapy treatment, at weekly time intervals.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Thermography
2006
N/A
~610

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1 year
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 1 year for reporting.

Who is running the study

Principal Investigator
D. W. T.
Dr. William Tran, MD
Sunnybrook Health Sciences Centre

Closest Location

Sunnybrook Hospital - Toronto, Canada

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
People who take part in this study must be able to understand and carry out the instructions given to them. show original
Some people with cancer in the head or neck may need surgery as their only treatment or as part of adjuvant treatment. show original
This is a type of radiation therapy that is used to treat cancer in the head and neck region. show original
The person has a biopsy-confirmed diagnosis of breast cancer (Stage 0-III) or head and neck cancer (all subtypes; stage I - IV) according to American Joint Committee on Cancer staging criteria. show original
Both men and women are eligible for participation
People must be over 18 to participate in the study. show original
breast conservation therapy with radiation Both radiation therapy options are effective at reducing the risk of the cancer returning. show original
, and they may choose to withdraw from the study at any time without penalty show original

Patient Q&A Section

Can radiodermatitis be cured?

"Radiodermatitis is a serious skin condition associated with an increasing volume of patient complaints at [any age] in the Western world, but even more so in Southern Europe and in the UK. With current treatment, however, it is curable." - Anonymous Online Contributor

Unverified Answer

What are the signs of radiodermatitis?

"Radiodermatitis is caused by the ionizing radiation of x-rays and radioisotopes, and the symptoms are quite nonspecific. Although many nonspecific symptoms exist, the most important signs are skin and mucous membrane involvement. This disease is a medical emergency, and dermatological referral is recommended." - Anonymous Online Contributor

Unverified Answer

How many people get radiodermatitis a year in the United States?

"The number of people with radiodermatitis for several reasons is significantly higher than that reported in medical literature. To our knowledge, this is the largest national survey of people with radiodermatitis. We should not ignore its seriousness and possible dangers." - Anonymous Online Contributor

Unverified Answer

What are common treatments for radiodermatitis?

"The treatment for radiodermatitis is quite varied. To assess the possible treatment alternatives that might be needed, this review of the literature should be helpful." - Anonymous Online Contributor

Unverified Answer

What is radiodermatitis?

"Radiodermatitis is an inflammation around a piece of ionizing radiation. It is not uncommon. It is often caused by imaging of the abdomen or pelvis. It can be distinguished by the presence of blisters on the skin after the radiation exposure." - Anonymous Online Contributor

Unverified Answer

What causes radiodermatitis?

"Aspects of radiodermatitis pathogenesis should be improved by utilizing the new imaging techniques. New radiologic evidence of inflammation can be detected using the diagnostic criteria. Radiodermatitis could be a common disease related to excessive exposure to ionizing radiation." - Anonymous Online Contributor

Unverified Answer

Does thermography improve quality of life for those with radiodermatitis?

"Thermography is a useful screening test to select patients for treatment options. It has a negative impact on health-related quality of life (SF-12) when compared to clinical evaluation. In addition, patients tended to attribute changes in health to treatment, rather than the disease itself. Therefore, it seems beneficial to use the patient's own method of evaluation to decide how to approach the disorder." - Anonymous Online Contributor

Unverified Answer

How does thermography work?

"Thermography appears to be a useful tool for the detection of radiation dermatitis and warrants further investigation as a method of monitoring patients after radiation therapy." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets radiodermatitis?

"The average age of diagnosis of radiodermatitis is about 46 yr. There is no clear consensus between medical specialties on the typical age of diagnosis, though most commonly the mean age of diagnosis is approximately 43 yr. Findings from a recent study highlights the need for earlier recognition and diagnostic treatment." - Anonymous Online Contributor

Unverified Answer

What is the latest research for radiodermatitis?

"Recent studies suggest the use of low-dose aspirin and alpha2-stimulating agents for radiation dermatitis prevention. In those patients who develop radiation dermatitis, treatment with aloe vera cream also proved effective in preventing its occurrence." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of thermography?

"Recent findings were consistent with those of previous clinical studies where the most common side effects reported in clinical case studies were irritation of the skin and minor burns to the eyes; the frequency and severity were related to the patient's age and the duration of time they had been exposed to the radiant heat." - Anonymous Online Contributor

Unverified Answer

Is thermography typically used in combination with any other treatments?

"In this group of patients with rheumatoid arthritis, thermography was used in combination with several different treatment interventions, which were found helpful and successful in controlling inflammation, relieving pain and disability of patients." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
See if you qualify for this trial
Get access to this novel treatment for Radiodermatitis by sharing your contact details with the study coordinator.