Thermal Imaging to Evaluate Skin Toxicity From Radiotherapy

Overseen By William T Tran, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Sunnybrook Health Sciences Centre

Disqualifiers: Dermatologic abnormalities, Connective tissue disease, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

200 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial uses a special camera to measure skin temperature changes in patients receiving radiotherapy for breast or head and neck areas. These patients often have skin problems due to their treatment. The camera helps doctors see how much skin damage has occurred by showing temperature differences.

Who Is on the Research Team?

William T Tran, PhD

Principal Investigator

Clinician Scientist

Are You a Good Fit for This Trial?

Inclusion Criteria

Biopsy-confirmed diagnosis of breast cancer (Stage 0-III) or head and neck cancer (all subtypes; stage I - IV) according to American Joint Committee on Cancer staging criteria.

Subjects must give appropriate written informed consent prior to participation in the study

Subjects must be able and willing to comply and understand the instructions associated with the imaging procedure.

Exclusion Criteria

Subjects with any pre-existing dermatologic abnormalities (open sores, keloids, psoriasis) involving the treated breast or head and neck.

Subjects who are pregnant or lactating (which usually preclude them from radiotherapy)

You have very hairy skin that prevents accurate measurement of heat output.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Radiotherapy Treatment

Participants undergo radiotherapy treatment with weekly thermal imaging to evaluate skin toxicity

1 year

Weekly visits for thermal imaging

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Thermography

How Is the Trial Designed?

Group I: Thermal Imaging Experimental Treatment 1 Intervention

Patients will undergo non-invasive, thermal imaging of their whole breast or head and neck cancer site, during the course of the radiotherapy treatment, at weekly time intervals.

Who Is Running the Clinical Trial?

Sunnybrook Health Sciences Centre

Lead Sponsor

Trials

693

Recruited

1,569,000+