Transcranial Magnetic Stimulation Device for Role of Sex Hormones in Neuromuscular Function

Phase-Based Progress Estimates
UT Southwestern Medical Center, Dallas, TXRole of Sex Hormones in Neuromuscular FunctionTranscranial Magnetic Stimulation Device - Device
18 - 39
All Sexes
What conditions do you have?

Study Summary

This trial seeks to understand how changes in sex hormones can affect muscle reflexes and motor control at different levels.

Treatment Effectiveness

Study Objectives

3 Primary · 2 Secondary · Reporting Duration: 2 months

1 month
Ovulation testing.
Sex hormone fluctuations on cortical excitability using transcranial magnetic stimulation (TMS).
2 months
Anterior knee laxity measurement.
H-reflex testing.
Polysynaptic reflex testing.
Sex hormone fluctuations on muscle stretch reflex at relaxed and active states.
Tendon tap reflex testing.

Trial Safety

Trial Design

1 Treatment Group

1 of 1

Experimental Treatment

70 Total Participants · 1 Treatment Group

Primary Treatment: Transcranial Magnetic Stimulation Device · No Placebo Group · N/A

Experimental Group · 1 Intervention: Transcranial Magnetic Stimulation Device · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 2 months

Who is running the clinical trial?

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NIH
453 Previous Clinical Trials
1,083,813 Total Patients Enrolled
University of Texas Southwestern Medical CenterLead Sponsor
962 Previous Clinical Trials
1,108,417 Total Patients Enrolled
Yasin Dhaher, Ph.D.Principal Investigator - UT Southwestern Medical Center
University of Texas Southwestern Medical Center

Eligibility Criteria

Age 18 - 39 · All Participants · 2 Total Inclusion Criteria

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Who else is applying?

What state do they live in?
How old are they?
18 - 65100.0%
What site did they apply to?
UT Southwestern Medical Center100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%

Frequently Asked Questions

What is the sample size for this research endeavor?

"Affirmative. The trial is actively recruiting according to information available on; the original post was published in April 12th 2019 and has been recently edited as of June 30th 2022. 70 participants are needed from a single site for this research study." - Anonymous Online Contributor

Unverified Answer

Could I be considered for admission into this research trial?

"This medical trial seeks 70 individuals aged 18-39 whose sex hormones interact with the neuromechanical axis. Female participants must fall within this age range and not have experienced a pregnancy before, in addition to having regular menstrual cycles of 24-35 days or be on an established hormonal contraceptive for 6 months (oral, transdermal or vaginal) as well as exercising moderately (less than 7 hours per week)." - Anonymous Online Contributor

Unverified Answer

Is the age criterion of 50 years or older a requirement for enrolment in this research?

"This medical trial seeks out candidates between the ages of 18 and 39." - Anonymous Online Contributor

Unverified Answer

Are participants being accepted for this clinical experiment at present?

"Affirmative. Records on confirm that this health study, having been initially uploaded on April 12th 2019, is actively seeking participants. Seventy patients are needed to be recruited from 1 particular medical centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.