← Back to Search

Device

Transcranial Magnetic Stimulation for Stroke (CAM Trial)

N/A
Recruiting
Led By George F. Wittenberg, MD PhD
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be 45-90 years of age
Stroke onset at least 6 months before enrollment
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediate (within 2 s after stimulation)
Awards & highlights

CAM Trial Summary

This trial is testing whether TMS can help people with stroke regain movement.

Who is the study for?
This trial is for English-speaking adults aged 45-90 who've had a stroke at least 6 months ago, resulting in mild to moderate arm dysfunction. They must be medically stable and have no serious illnesses that would affect participation. People with visual loss, joint motion issues, or conditions preventing safe TMS/MRI use cannot join.Check my eligibility
What is being tested?
The study uses Transcranial Magnetic Stimulation (TMS) while participants make movements with a robotic arm device to understand how the brain controls movement before and after a stroke and when it's most responsive to TMS.See study design
What are the potential side effects?
TMS may cause discomfort at the stimulation site, headache, lightheadedness, or seizures in very rare cases. It's generally considered safe but should be avoided by those with certain medical implants.

CAM Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 45 and 90 years old.
Select...
I had a stroke more than 6 months ago.
Select...
I had a stroke in a deep part of my brain.
Select...
I am medically stable enough to join the study.
Select...
I have some difficulty moving my arm.
Select...
I had a stroke that affects one side of my body and other causes have been ruled out.

CAM Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediate (within 2 s after stimulation)
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediate (within 2 s after stimulation) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Path length
Secondary outcome measures
Accuracy
EMG
Times
+1 more

CAM Trial Design

1Treatment groups
Experimental Treatment
Group I: Reaching with TMSExperimental Treatment1 Intervention
All participants enrolled in this group will receive TMS while performing reaching movements in a robotic system.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation
2011
Completed Phase 4
~710

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,606 Previous Clinical Trials
3,305,988 Total Patients Enrolled
83 Trials studying Stroke
6,701 Patients Enrolled for Stroke
VA Pittsburgh Healthcare SystemFED
32 Previous Clinical Trials
11,392 Total Patients Enrolled
2 Trials studying Stroke
2 Patients Enrolled for Stroke
University of PittsburghOTHER
1,716 Previous Clinical Trials
16,346,437 Total Patients Enrolled
26 Trials studying Stroke
2,687 Patients Enrolled for Stroke

Media Library

Transcranial Magnetic Stimulation (Device) Clinical Trial Eligibility Overview. Trial Name: NCT04286516 — N/A
Stroke Research Study Groups: Reaching with TMS
Stroke Clinical Trial 2023: Transcranial Magnetic Stimulation Highlights & Side Effects. Trial Name: NCT04286516 — N/A
Transcranial Magnetic Stimulation (Device) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04286516 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any spots available for enrollment in this experiment?

"Indeed, the clinical trial is still recruiting based on information available through clinicaltrials.gov. The study was inaugurated on January 10th 2020 and updated June 3rd 2022 - it requires 6 participants to be sourced from one medical centre."

Answered by AI

Are participants younger than 30 years old allowed to take part in the research?

"The minimum age for entry into the trial is 45, with a cut-off of 90 years old."

Answered by AI

Am I eligible to participate in this medical experiment?

"This medical research is targeting 6 individuals aged 45 to 90 with nervous system disorders. In order to qualify, potential participants must have a unilateral hemiparetic stroke that has been radiologically confirmed, demonstrate sufficient linguistic and cognitive abilities for training and testing, be medically stable enough to partake in the study, possess English proficiency as their native language, experienced a subcortical stroke such as an internal capsule or deep white matter of posterior frontal lobe at least six months before recruitment began , present mild-to-moderate arm dysfunction symptoms, and be between 45-90 years old."

Answered by AI

What is the scope of enrollees for this clinical experiment?

"Affirmative. The clinical trial, which was initially posted on 10th January 2020, is currently recruiting participants and was last updated on 3rd June 2022. 6 individuals are needed from 1 medical centre to complete the study."

Answered by AI
Recent research and studies
~4 spots leftby Jun 2025