Transcranial Magnetic Stimulation for Stroke

Recruiting · 18+ · All Sexes · Pittsburgh, PA

This study is evaluating whether a magnetic pulse to the brain can help improve movement for individuals who have had a stroke.

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About the trial for Stroke

Eligible Conditions
Stroke · Brain Diseases · Central Nervous System Diseases · Nervous System Diseases · Cardiovascular Diseases

Treatment Groups

This trial involves 2 different treatments. Transcranial Magnetic Stimulation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Transcranial Magnetic Stimulation
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.

About The Treatment

First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation
Completed Phase 4


This trial is for patients born any sex aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
excluded People who had a stroke six months or more before enrolling in the study were excluded. show original
Be between 45 and 90 years old. show original
Have adequate language and neurocognitive function to participate in training and testing
A stroke that affects only one side of the body and can be ruled out as something else using imaging techniques. show original
A stroke involving the internal capsule or deep white matter of the posterior frontal lobe. show original
Present with mild to moderate arm dysfunction
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: Immediate (within 2 s after stimulation)
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: Immediate (within 2 s after stimulation).
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Transcranial Magnetic Stimulation will improve 1 primary outcome and 4 secondary outcomes in patients with Stroke. Measurement will happen over the course of Immediate (within 2 s after stimulation).

specific position data from KINARM system: target accuracy, distance from manipulandum position at end of one second reaching period to target center. (units: cm.)
Path length
Movement path length in centimeters from KINARM system during the one second reaching period. (units: cm)
Electromyographic data from surface electrodes on biceps, triceps, anterior deltoid, and posterior deltoid muscles - These signals will be rectified and normalized to the maximum values during practice reaches. (units: mV/mV - dimensionless).
maximum velocity reached during reach (units: cm/s)
Specific kinematic data from KINARM system: reaction time, movement time to reach target (units: ms)

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many people get stroke a year in the United States?

About 936,000 people per year in the United States are admitted to hospital with a stroke. This makes stroke the third most common cause of brain damage in the United States.

Anonymous Patient Answer

What causes stroke?

Stroke is an important neurological illness; its symptoms may be associated with a number of causes. The underlying pathophysiology of stroke is complex and may be better understood by examining specific factors such as age, stroke risk factors, stroke size, and stroke mechanisms.

Anonymous Patient Answer

What are common treatments for stroke?

Unlike hypertension, in which treatment varies inversely with the level of stroke severity, treatment regimens for stroke (including stroke units) converge in a unified set of interventions for acute stroke patients and recommendations for outpatient follow-up. Stroke has considerable potential for cost-cutting.

Anonymous Patient Answer

Can stroke be cured?

There are no cures, but we can manage symptoms by restricting the activity level and getting the patient to take a drug treatment such as aspirin, paracetamol, or nonsteroidal anti-inflammatory drugs (NSAIDS) for pain. The symptoms may subside after 3 to 4 days, but treatment is usually continued for six to seven months until the condition stabilises and the patient seems better able to function socially and professionally.

Anonymous Patient Answer

What are the signs of stroke?

If there is a sudden onset of one side of the body and there is swelling or bleeding on the affected side of the torso, or an area of the chest wall on one side is swollen and has tenderness. There may be numbness or weakness in the arm or leg. There may also be double vision or trouble hearing. Complications of stroke such as trouble swallowing (dysphagia), inability to talk as well as other effects may appear.\n

Anonymous Patient Answer

What is stroke?

Symptoms of stroke may include numbness and tingling sensations at the site of the stroke, sudden weakness in one extremity, loss of function and sensation in one or more areas of the body, difficulty in talking or walking, inability to swallow or breathe, and sudden confusion or loss of awareness. A person with stroke suffers from various symptoms which may vary over time. The symptoms are related to the person's age, severity and location of the stroke, preexisting health problems, and whether the symptoms occur together or not. Strokes can affect one side of the brain, both sides at once, or be bilateral, occurring on both sides of the brain.

Anonymous Patient Answer

What is the latest research for stroke?

The most significant advances in recent years in research are related to thrombolytic therapy, tissue plasminogen activator (TPA) and angiographic imaging. The best therapy for hemorrhagic strokes appears to be TPA (tissue plasminogen activator). The angiographic imaging can also be utilized in stroke management.

Anonymous Patient Answer

How serious can stroke be?

My friend, a well-known doctor called to tell me that his son has suffered from a moderate ischaemic stroke. He has walked with assistance, and some balance without any help. He was advised to take aspirin, but he wanted to try other medicines; we then asked his wife, he was admitted for check-ups at the hospital and his stroke was confirmed and we had to find out the culprits. At our patient's request we prescribed him Naturopathy for strokes in 1 month with the next visit. I asked the doctor a lot of questions about the course of stroke and his diagnosis.

Anonymous Patient Answer

What does transcranial magnetic stimulation usually treat?

Using an expert panel to evaluate the clinical applications of TMS on a regular basis is a helpful tool to identify the patient group who will benefit most from TMS.

Anonymous Patient Answer

Does stroke run in families?

The risk for first-ever stroke was highest among relatives of patients with atherothrombotic disease. In a recent study, findings suggest that there may be some common familial determinant for arterial and venous strokes within the same family.

Anonymous Patient Answer

Has transcranial magnetic stimulation proven to be more effective than a placebo?

tms was as effective as placebo. It could be considered for the treatment of post-stroke headaches. However, the sample size was too small to make a definite determination and, because we did not assess the effect of treatment on the size of the lesion, future investigation on cortical excitability in patients with post-stroke headache is needed.

Anonymous Patient Answer
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