Study Summary
This trial will study the effects of opioids and sedatives, alone and in combination, on people's ratings of drug liking and other abuse-related effects, as well as on physiological outcomes.
- Opioid Use Disorder
- Sedative Use
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 3 Secondary · Reporting Duration: These outcomes (visual analog scores, scale of 0-100) will be recorded prior to and in regular intervals after drug administration for the duration of the session (approx. 8 hours per session).
Trial Safety
Phase-Based Safety
Side Effects for
Awards & Highlights
Trial Design
3 Treatment Groups
Oral sedative
1 of 3
Oral opioid agonist
1 of 3
Opioid agonist/sedative
1 of 3
Experimental Treatment
72 Total Participants · 3 Treatment Groups
Primary Treatment: Sedatives · No Placebo Group · Phase 1
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 55 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Is the minimum age for participation in this medical research set at 18 or below?
"This trial only accepts patients 18 to 55 years old. For minors and seniors, there are 14 trials available for the former cohort and 120 studies open to those above 65 years of age." - Anonymous Online Contributor
What is the maximum capacity at which this clinical trial can be conducted?
"Correct. Clinicaltrials.gov documents that this research is actively enrolling participants, with the original post date being March 25th 2019 and a recent edit on November 17th 2022. 72 volunteers are needed at one location for the clinical trial to be successful." - Anonymous Online Contributor
Are there opportunities for enrolment in this research project currently?
"Affirmative. Per the information found on clinicaltrials.gov, this medical trial is currently enrolling participants which were initially posted back in March of 2019 and was last updated on November 17th 2022. 72 patients are needed to be recruited from 1 site." - Anonymous Online Contributor
Would I be qualified to join this clinical trial?
"This observational research is recruiting 72 individuals aged 18 to 55, and the requisite criteria for enrollment involves past or present non-medicinal consumption of opioids and sedative medications." - Anonymous Online Contributor
To what extent are sedatives deemed safe for human consumption?
"Although limited data on the efficacy and safety of sedatives is available, our team at Power assigned a score of 1 to this phase 1 trial." - Anonymous Online Contributor