← Back to Search

Cannabinoid

Marijuana + Opioid Interaction for Substance Use Disorders

Q: Does the use of cannabis carry any notable risks for patients?

<p>Given the limited available data on <a href="https://www.withpower.com/clinical-trials/marijuana">Marijuana</a>'s safety and efficacy, our team has assigned it a rating of 1.</p>

Phase 1

Recruiting

Research Sponsored by Shanna Babalonis, PhD

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Ages 18-50

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, post-dose during each session (change from baseline is assessed); visual analog scales will be the primary measure (0-100, 0=not at all, 100=extremely)

Awards & highlights

Study Summary

This trial examines how marijuana and oxycodone affect each other when taken together, and at different doses.

Who is the study for?

This trial is for adults aged 18-50 who have used marijuana and opioids before, are generally healthy, and can stay at the University of Kentucky Hospital research unit for about 6.5 weeks with meals provided. People with significant medical conditions cannot participate.Check my eligibility

What is being tested?

The study is looking into how marijuana affects the use of oxycodone (a type of opioid) and vice versa. Participants will be given different doses of each drug in a controlled environment to see how one influences the desire or effects of the other.See study design

What are the potential side effects?

Possible side effects may include drowsiness, dizziness, nausea, confusion from opioids; and dry mouth, red eyes, increased appetite or short-term memory issues from marijuana.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 50 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, post-dose during each session (change from baseline is assessed)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, post-dose during each session (change from baseline is assessed)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post-dose during each session (change from baseline is assessed) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Self-Administration

Secondary outcome measures

Blood pressure

Heart rate

Subjective measures

Trial Design

2Treatment groups

Experimental Treatment

Group I: Double-blind opioid/placebo administrationExperimental Treatment2 Interventions

Participants will receive double-blind administration of intranasal opioid agonist/placebo

Group II: Double-blind marijuana/placebo administrationExperimental Treatment2 Interventions

Participants will receive double-blind administration of vaporized marijuana/placebo

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Marijuana

2008

Completed Phase 2

~360

Opioid

2008

Completed Phase 4

~2450

0 / 1Eligibility criteria met

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Shanna Babalonis, PhDLead Sponsor

2 Previous Clinical Trials

43 Total Patients Enrolled

1 Trials studying Cannabis Use

34 Patients Enrolled for Cannabis Use

National Institute on Drug Abuse (NIDA)NIH

2,470 Previous Clinical Trials

2,619,719 Total Patients Enrolled

29 Trials studying Cannabis Use

6,388 Patients Enrolled for Cannabis Use

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the use of cannabis carry any notable risks for patients?

"Given the limited available data on Marijuana's safety and efficacy, our team has assigned it a rating of 1."

Answered by AI

What criteria must one meet to be considered a viable candidate for this clinical trial?

"To meet the requirements of this study, applicants must have a history of cannabis consumption and be between 18 to 50 years old. This medical trial is presently looking for 12 individuals for participation."

Answered by AI

Are there any recruitment opportunities available for individuals interested in participating in this trial?

"According to clinicaltrials.gov, this medical trial is actively seeking out candidates for participation. It was original posted on August 3rd 2023 and has been refreshed as recently as October 27th of the same year."

Answered by AI

Is this clinical experiment open to participants aged 35 and above?

"This research trial is open to applicants aged between 18 and 50. Nonetheless, there are 30 studies designated for minors (under 18) and 157 trials specifically dedicated to those over 65 years old."

Answered by AI

How many participants are being enrolled in this investigation?

"Affirmative, the information on clinicaltrials.gov manifest that this investigation is currently recruiting patients. The initial posting was made on August 3rd 2023 and has been amended as of October 27th 2023. A total of 12 participants are needed across a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Reinforcing Effects of Marijuana and Opioids

Shanna Babalonis, PhD 2023. "Reinforcing Effects of Marijuana and Opioids". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05485012.

All > Opiate Addiction > Cannabis