Study Summary
This trial will study the effects of alcohol and opioids, alone and in combination. The primary outcomes are subjective ratings of drug liking and other abuse-related effects; physiological outcomes.
- Alcohol Consumption
- Opioid Use Disorder
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 3 Secondary · Reporting Duration: These outcomes (visual analog scores, scale of 0-100) will be recorded prior to and in regular intervals after drug administration for the duration of the session (approx. 6.5 hours per session)
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
3 Treatment Groups
Opioid Agonist
1 of 3
Alcohol
1 of 3
Opioid Agonist/Alcohol Combination
1 of 3
Experimental Treatment
72 Total Participants · 3 Treatment Groups
Primary Treatment: Opioid Agonist · No Placebo Group · Phase 1
Trial Logistics
Logistics
Participation is compensated
You will be compensated for participating in this trial.
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 21 - 55 · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Kentucky | 100.0% |
How old are they?
| 18 - 65 | 100.0% |
What site did they apply to?
| University of Kentucky | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
Frequently Asked Questions
What types of illnesses are treated by Opioid Agonists?
"Opioid Agonist is a common treatment for obstructive hypertrophic cardiomyopathy, and can also be useful in combating communicable diseases, ethylene glycol toxicity, as well as disinfecting the skin." - Anonymous Online Contributor
Am I eligible to get involved in this research endeavor?
"This research is hoping to recruit 72 individuals aged 21 and 55 who have a history of alcohol consumption. To be eligible, candidates should exhibit non-medicinal opioid use, prior alcoholic habits, and fall within the aforementioned age range." - Anonymous Online Contributor
Has the FDA approved Opioid Agonist as a therapeutic treatment?
"Our safety assessment of opioid agonist, based on the limited data from phase 1 trials, resulted in a rating of 1." - Anonymous Online Contributor
How many individuals are participating in this scientific experiment?
"That is correct. Records on clinicaltrials.gov indicate that recruitment for this trial, which was first published in March 2021, is still ongoing. Aiming to include 72 individuals, the research site currently requires enrolment from one location only." - Anonymous Online Contributor
Are any new participants being accepted for this trial?
"Affirmative. According to the information posted on clinicaltrials.gov, this medical trial is currently searching for participants and was originally published on March 24th 2021. Updating most recently on October 28th 2022, it aims to enroll 72 patients from a single location." - Anonymous Online Contributor
Is eligibility for this trial restricted to those above a certain age?
"This investigation is open to those of legal age and under 55 years old." - Anonymous Online Contributor