Essential Thrombocythemia Clinical Trials
Here are the 6 most popular medical studies for essential thrombocythemia
Alkylating agents
Topotecan Hydrochloride +2 More for Chronic Myelomonocytic Leukemia
This trial is testing how well topotecan hydrochloride, carboplatin, and veliparib work in treating patients with myeloproliferative disorders and acute myeloid leukemia or chronic myelomonocytic leukemia.
Janus Kinase (JAK) Inhibitor
Ruxolitinib + Azacytidine for Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm
This trial is testing a combination of two drugs to treat patients with myelofibrosis or myelodysplastic syndrome/myeloproliferative neoplasm.
Popular filter options for essential thrombocythemia trials
Myelofibrosis Clinical Trials
View 26 Myelofibrosis medical studies.
JAK2 Inhibitor
Pacritinib for Myelofibrosis
This trial is testing a new drug, pacritinib, to see if it is better than the current standard of care for treating patients with primary myelofibrosis, post-polycythemia vera myelofibrosis, or post-essential thrombocythemia myelofibrosis who have severe thrombocytopenia (low platelet count). 399 patients will be enrolled and randomly assigned to either pacritinib or the current standard of care. The primary outcome measure is spleen response rate.
Anti-metabolites
Decitabine + JAK Inhibitors for Advanced Myeloproliferative Disorders
This trial looks at whether a combination of decitabine, ruxolitinib, and fedratinib may be more effective than chemotherapy or no treatment in patients with myeloproliferative neoplasms.
Primary Myelofibrosis Clinical Trials
View 20 Primary Myelofibrosis medical studies.
JAK2 Inhibitor
Pacritinib for Myelofibrosis
This trial is testing a new drug, pacritinib, to see if it is better than the current standard of care for treating patients with primary myelofibrosis, post-polycythemia vera myelofibrosis, or post-essential thrombocythemia myelofibrosis who have severe thrombocytopenia (low platelet count). 399 patients will be enrolled and randomly assigned to either pacritinib or the current standard of care. The primary outcome measure is spleen response rate.
Anti-metabolites
Decitabine + JAK Inhibitors for Advanced Myeloproliferative Disorders
This trial looks at whether a combination of decitabine, ruxolitinib, and fedratinib may be more effective than chemotherapy or no treatment in patients with myeloproliferative neoplasms.
Essential Thrombocythemia Clinical Trials With No Placebo
View 36 essential thrombocythemia medical studies that do not have a placebo group.
Interferon
Ropeginterferon Alfa-2b for Essential Thrombocythemia
This trial is testing a new drug, P1101, to see if it is more effective and has fewer side effects than the current standard drug, ANA, for treating people with essential thrombocythemia who have not responded well to hydroxyurea.
View More Essential Thrombocythemia Trials
See another 16 medical studies focused on essential thrombocythemia.
Frequently Asked Questions
Introduction to essential thrombocythemia
What are the top hospitals conducting essential thrombocythemia research?
When it comes to cutting-edge clinical trials focused on essential thrombocythemia, several top hospitals are leading the way. In Ann Arbor, Michigan, the University of Michigan is at the forefront with three active trials dedicated to this condition and a total of ten previous studies. Their commitment to advancing our understanding of essential thrombocythemia began in 2011 when they recorded their first trial. Meanwhile, in Houston, Texas, two renowned institutions are making significant contributions as well. The University of Texas MD Anderson Cancer Center has two ongoing essential thrombocythemia trials and a solid track record of seven past studies since their inaugural trial in 2014. Another notable presence is the MD Anderson Cancer Center located in Houston too where they currently have two active essential thrombocythemia trials building upon their twelve previous investigations which dates back till2007.The Icahn School of Medicine at Mount Sinai in New york joins this esteemed group with two ongoing clinical trials for essential thrombocythemia and an impressive history that includes eighteen completed studies since 2007.Further adding depth to these research efforts,Fred Hutchinson Cancer Research Center based out Seattlealso contributes significantly through its current participationin two trails surrounding the condition while having executed seven such tests on patients relatedto this ailment ever since year 2007.
These top-tier hospitals not only offer hope for those affected by essential thrombocythemia but also serve as beacons of medical progress across different regions.Highlights from these centers illustrate that despite being a relatively rare blood disorder characterized by excessive platelet production,the collective endeavors towards understanding and treatingessential trombocthemiaspans across diverse geographic locations;the tireless dedication displayedby multiple institutionsspeaks volumes abouttheir resolveintendingtopaving new avenuesfor improved treatmentthat guaranteea better qualityof life foraffected individuals aroundtheworld
Which are the best cities for essential thrombocythemia clinical trials?
When it comes to essential thrombocythemia clinical trials, several cities emerge as leaders in research and development. New york, Ann Arbor, Houston, San Antonio, and Montreal all have active trials focused on advancing our understanding and treatment of this condition. These trials investigate promising therapies such as FEDRATINIB, Ropeginterferon alfa-2b, KRT-232, Bomedemstat, PXS-5505, IMG-7289 and Pacritinib. With a combined total of 27 ongoing studies across these cities alone, individuals with essential thrombocythemia can access cutting-edge clinical trials that may lead to improved outcomes and quality of life.
Which are the top treatments for essential thrombocythemia being explored in clinical trials?
Exciting developments in essential thrombocythemia research have brought forward several potential treatments currently being explored in clinical trials. Leading the charge is IMG-7289, which has shown promise in two active trials and features prominently among the three all-time essential thrombocythemia trials since its introduction in 2017. Another contender making waves is bomedemstat, currently involved in one active trial and appearing on two all-time essential thrombocythemia studies list, having made its debut just last year. Also gaining attention is PXS-5505, with one ongoing trial dedicated to exploring its efficacy against this condition since its listing earlier this year. Last but not least is KRT-232, featured in one active trial and included within three crucial all-time essential thrombocythemia studies after hitting the scene back in 2019. These innovative treatment options offer hope to patients battling essential thrombocythemia as researchers continue their relentless pursuit of effective solutions for this rare blood disorder.
What are the most recent clinical trials for essential thrombocythemia?
Exciting advancements are underway in the field of essential thrombocythemia, with recent clinical trials shedding light on potential treatments. One such trial focuses on bomedemstat, a promising drug being evaluated for its effectiveness against this condition. Another study investigates the use of PXS-5505 as a treatment option, aiming to improve patient outcomes and quality of life. Additionally, KRT-232 is undergoing testing to determine its efficacy in addressing essential thrombocythemia. These studies represent significant strides towards finding better therapeutic options for individuals affected by this disorder.
What essential thrombocythemia clinical trials were recently completed?
Recently conducted clinical trials have contributed to the advancement of treatments for essential thrombocythemia, a rare disorder characterized by an excess of platelets in the blood. Notably, John Mascarenhas led a trial exploring the potential of AVID200 and completed it in February 2019. Similarly, Imago BioSciences concluded their investigation into IMG-7289 in July 2017. Additionally, M.D. Anderson Cancer Center wrapped up their study on Smac Mimetic LCL161 back in December 2014. These important trials signify ongoing efforts to improve outcomes and quality of life for individuals affected by essential thrombocythemia.