Bomedemstat for Myeloproliferative Disorders
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing the safety and effectiveness of bomedemstat, a daily oral medication, in patients with a blood disorder called MPN. The drug works by controlling blood cell production.
Do I need to stop taking my current medications for the trial?
You may need to stop taking certain medications, as the trial excludes participants using prohibited medications like romiplostim. It's best to discuss your current medications with the trial team to see if any need to be stopped.
How is the drug Bomedemstat unique for treating myeloproliferative disorders?
What data supports the effectiveness of the drug Bomedemstat for treating myeloproliferative disorders?
Who Is on the Research Team?
Medical Director
Principal Investigator
Merck Sharp & Dohme LLC
Are You a Good Fit for This Trial?
This trial is for patients with myeloproliferative disorders who have already completed a treatment period in a previous bomedemstat study. They must be assessed by the investigator as suitable for continued dosing and agree to use contraception. Excluded are those on certain medications, unable to consent or comply, pregnant or breastfeeding women, participants in other trials, and anyone non-compliant in past studies.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive bomedemstat daily for 169 days with additional treatment continuing in participants deriving clinical benefit
Follow-up
Participants are monitored for safety and effectiveness after treatment
Open-label extension
Participants continue to receive bomedemstat to assess long-term safety and efficacy
What Are the Treatments Tested in This Trial?
Interventions
- Bomedemstat
Find a Clinic Near You
Who Is Running the Clinical Trial?
Imago BioSciences,Inc.
Lead Sponsor
Imago BioSciences, Inc., a subsidiary of Merck & Co., Inc., (Rahway, New Jersey USA)
Lead Sponsor