Study Summary
This trial is testing if reducing inflammation through exercise can help improve vascular function in obese people.
Eligible Conditions
- Obesity
- Vascular Dysfunction
Treatment Effectiveness
Phase-Based Effectiveness
N/A
Study Objectives
1 Primary · 2 Secondary · Reporting Duration: Month 24-30
Month 1-20
Flow induced dilation
Month 24-30
DNA methylation status of adipocytokines in obese individuals
Vascular health biomarkers in obese individuals before and after exercise training
Trial Safety
Phase-Based Safety
Awards & Highlights
No Placebo Group
All patients enrolled in this trial will receive the new treatment.
Trial Design
2 Treatment Groups
Exercising
1 of 2
Non-exercising
1 of 2
Active Control
80 Total Participants · 2 Treatment Groups
Primary Treatment: Exercising · No Placebo Group · N/A
Exercising
Other
ActiveComparator Group · 1 Intervention: Exercise training · Intervention Types: OtherNon-exercisingNoIntervention Group · 1 Intervention: Non-exercising · Intervention Types:
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: month 24-30
Who is running the clinical trial?
University of Illinois at ChicagoLead Sponsor
557 Previous Clinical Trials
1,553,932 Total Patients Enrolled
31 Trials studying Obesity
9,635 Patients Enrolled for Obesity
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,674 Previous Clinical Trials
47,133,830 Total Patients Enrolled
246 Trials studying Obesity
203,811 Patients Enrolled for Obesity
Abeer Mohamed, MD, PhDPrincipal InvestigatorUniversity of Illinois at Chicago
Eligibility Criteria
Age 18 - 50 · All Participants · 4 Total Inclusion Criteria
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