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MOx Diet for Enteric Hyperoxaluria

N/A
Recruiting
Led By David Goldfarb, MD
Research Sponsored by NYU Langone Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Subjects > 18 years and < 80 years of age
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 23-24
Awards & highlights

Study Summary

This trial will test the effects of a high oxalate diet on subjects with IBD or who have had gastric bypass surgery.

Who is the study for?
Adults aged 18-80 with IBD or post-RYGB surgery, who've had a kidney stone or related event in the last three years can join. It's open to all races and genders but not for pregnant/nursing women, those with recent antibiotics use, colectomy patients, active IBD flare-ups, or significantly impaired kidney function.Check my eligibility
What is being tested?
The trial tests how a high oxalate diet affects individuals with Enteric Hyperoxaluria compared to healthy controls. Participants will follow specific diets and undergo stool and urine collections, blood tests, and intestinal health assessments at Weil Cornell Medicine.See study design
What are the potential side effects?
Potential side effects may include gastrointestinal discomfort due to the high oxalate diet such as bloating or constipation. There might also be an increased risk of forming new kidney stones during the study period.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 80 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 23-24
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 23-24 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Urinary Oxalate Levels (UOx)
Secondary outcome measures
Calcium Oxalate (CaOx) Supersaturation Levels
Plasma Oxalate Levels
Sucralose Levels
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Enteric HyperoxaluriaExperimental Treatment1 Intervention
Group II: Healthy ControlsActive Control1 Intervention

Find a Location

Who is running the clinical trial?

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,359 Previous Clinical Trials
4,314,511 Total Patients Enrolled
1 Trials studying Enteric Hyperoxaluria
114 Patients Enrolled for Enteric Hyperoxaluria
NYU Langone HealthLead Sponsor
1,369 Previous Clinical Trials
840,555 Total Patients Enrolled
Lama Nazzal, MDStudy ChairNYU Langone Health

Media Library

Moderately High Oxalate (MOx) Diet Clinical Trial Eligibility Overview. Trial Name: NCT05124886 — N/A
Enteric Hyperoxaluria Research Study Groups: Healthy Controls, Enteric Hyperoxaluria
Enteric Hyperoxaluria Clinical Trial 2023: Moderately High Oxalate (MOx) Diet Highlights & Side Effects. Trial Name: NCT05124886 — N/A
Moderately High Oxalate (MOx) Diet 2023 Treatment Timeline for Medical Study. Trial Name: NCT05124886 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this study encompass elderly patients?

"This medical trial is open to individuals aged 18 or above and younger than 80."

Answered by AI

How many individuals have enrolled in this clinical experiment?

"Accurate. Clinicaltrials.gov hosts data which verifies that the recruitment of patients for this trial is ongoing, starting from November 10th 2022 and last updated on the same date. As part of its goals, 80 people must be enrolled at a single medical centre."

Answered by AI

Are people currently allowed to participate in this research experiment?

"Affirmative. Clinicaltrials.gov affirms that this research project, which was first advertised on November 10th 2022, is actively recruiting participants. The trial needs 80 patients from 1 clinical site to be enrolled."

Answered by AI

What is the criteria for enrollment in this medical experiment?

"This medical research will include 80 people aged 18 to 80 with enteric hyperoxaluria. In addition, they must meet the following criteria: current diagnosis of inflammatory bowel disease or at least 6 months post-gastric bypass surgery; a recent episode of renal colic, emergency room visits, or urological interventions; evidence on imaging scans (CT scan, MRI, ultrasounds) of kidney stones in the past three years. All races and genders are accepted as well as healthy individuals without chronic diseases who have never taken any long term medications nor had GI issues related to urinary stone disease previously."

Answered by AI
~35 spots leftby Jun 2025