DAPPER for Pain

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Pain+8 More
DAPPER - Behavioral
Eligibility
18+
Female
What conditions do you have?
Select

Study Summary

This trial will help African American women 50+ years old who are experiencing depressive symptoms, pain, and difficulty with mobility. The DAPPER intervention study consists of 8 nurse visits to the participants' homes. These visits will help the participants with their pain and mood.

Eligible Conditions
  • Pain
  • Frailty
  • Weakness
  • Aging
  • Mental Depression

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

4 Primary · 4 Secondary · Reporting Duration: Baseline, 12 weeks and 24 weeks

Week 24
Change in Communication with Health Care Providers as assessed by the Patients' Reaction Assessment
Change in Comorbid Conditions as assessed by the Charlson Comorbidity Index
Change in Depressive Symptoms as assessed by the PROMIS 57
Change in Depressive Symptoms as assessed by the Patient Health Questionnaire 9 (PHQ-9)
Change in Frailty as assessed by the Frail Scale
Change in Frailty as assessed by the Frailty Phenotype measure
Change in Pain Intensity as assessed by the Patient Reported Outcomes Measurement Information System (PROMIS)
Change in Pain Interference as assessed by the PROMIS Pain Interference
Change in Physical Function as assessed by the Katz Activities of daily living (ADL)
Change in Physical Function as assessed by the Lawton's Instrumental Activities of Daily Living (IADL)
Change in Self Efficacy as assessed by the Coping and Self-Efficacy Scale
Change in Social engagement as assessed by the Social Network Scale
Change in Stress as assessed by the Perceived Stress Scale
Change in interleukin (IL)-1 beta in saliva (pg/ml)
Change in interleukin (IL)-6 in saliva (pg/ml)
Change in interleukin (IL)-8 in saliva (pg/ml)
Change in tumor necrosis factor (TNF)-alpha in saliva (pg/ml)

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Wait List Control Arm
1 of 2
Intervention Arm
1 of 2

Active Control

Experimental Treatment

32 Total Participants · 2 Treatment Groups

Primary Treatment: DAPPER · No Placebo Group · N/A

Intervention Arm
Behavioral
Experimental Group · 1 Intervention: DAPPER · Intervention Types: Behavioral
Wait List Control Arm
Behavioral
ActiveComparator Group · 1 Intervention: DAPPER · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 12 weeks and 24 weeks

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,055 Previous Clinical Trials
30,975,382 Total Patients Enrolled
22 Trials studying Pain
3,065 Patients Enrolled for Pain
Robert Wood Johnson FoundationOTHER
147 Previous Clinical Trials
677,612 Total Patients Enrolled
1 Trials studying Pain
750 Patients Enrolled for Pain
National Institute on Aging (NIA)NIH
1,383 Previous Clinical Trials
3,447,567 Total Patients Enrolled
7 Trials studying Pain
1,962 Patients Enrolled for Pain
Janiece L Taylor, PhDPrincipal InvestigatorJohns Hopkins School of Nursing
1 Previous Clinical Trials
30 Total Patients Enrolled

Eligibility Criteria

Age 18+ · Female Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Statement: I identify as an African American or black female
If you want to live in a community dwelling, you can choose from a variety of options
People who are pre-frail or frail have at least one or three of the following symptoms: low energy, poor endurance, slow walking speed, unintentional weight loss, poor balance, and low muscle mass.
Many people suffer from pain that lasts longer than 3 months and keeps them from doing the things they want to do
Complete the PHQ-9 at the screening call and then at the first visit.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 26th, 2021

Last Reviewed: November 26th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

Who else is applying?

What state do they live in?
Maryland100.0%
How old are they?
65+100.0%
What site did they apply to?
Johns Hopkins School of Nursing100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%

How responsive is this trial?

Most responsive sites:
  1. Johns Hopkins School of Nursing: < 48 hours
Average response time
  • < 2 Days
Typically responds via
Phone Call100.0%