← Back to Search

Behavioral Intervention

DAPPER Intervention for Depression and Pain (DAPPER Trial)

N/A
Recruiting
Led By Janiece L Taylor, PhD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
One ADL or IADL limitation
Self-report pain >3 out of a 0 -10 scale that has lasted longer than 3 months and keeps subjects from doing at least one activity that subjects would like to do
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 12 weeks and 24 weeks
Awards & highlights

DAPPER Trial Summary

This trial will help African American women 50+ years old who are experiencing depressive symptoms, pain, and difficulty with mobility. The DAPPER intervention study consists of 8 nurse visits to the participants' homes. These visits will help the participants with their pain and mood.

Who is the study for?
This trial is for African American women over 50 who live at home, have some difficulty with daily activities due to frailty, experience persistent pain that interferes with their activities, and show signs of depression. They should not be in physical therapy or have severe mental impairment.Check my eligibility
What is being tested?
The DAPPER intervention involves eight home visits by a nurse to assist participants with managing pain and improving mood. It's designed specifically for older African American women struggling with mobility due to pain and depression.See study design
What are the potential side effects?
Since the DAPPER intervention is non-pharmaceutical, focusing on nursing support rather than medication, specific side effects are not anticipated as commonly seen in drug trials.

DAPPER Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I need help with at least one daily activity.
Select...
I have pain over 3/10 that stops me from doing activities and it's lasted more than 3 months.

DAPPER Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 12 weeks and 24 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 12 weeks and 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Depressive Symptoms as assessed by the PROMIS 57
Change in Depressive Symptoms as assessed by the Patient Health Questionnaire 9 (PHQ-9)
Change in Pain Intensity as assessed by the Patient Reported Outcomes Measurement Information System (PROMIS)
+1 more
Secondary outcome measures
Change in Frailty as assessed by the Frail Scale
Change in Frailty as assessed by the Frailty Phenotype measure
Change in Physical Function as assessed by the Katz Activities of daily living (ADL)
+1 more
Other outcome measures
Change in Communication with Health Care Providers as assessed by the Patients' Reaction Assessment
Change in Comorbid Conditions as assessed by the Charlson Comorbidity Index
Change in Self Efficacy as assessed by the Coping and Self-Efficacy Scale
+6 more

DAPPER Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Intervention ArmExperimental Treatment1 Intervention
The intervention group will receive the intervention for 12 weeks. The wait list control group will have outcomes measured but will not receive the intervention at this time.
Group II: Wait List Control ArmActive Control1 Intervention
Once the intervention group has completed the intervention the wait list control group will complete the intervention.

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,264 Previous Clinical Trials
14,823,145 Total Patients Enrolled
57 Trials studying Depression
29,583 Patients Enrolled for Depression
Robert Wood Johnson FoundationOTHER
157 Previous Clinical Trials
686,802 Total Patients Enrolled
15 Trials studying Depression
7,096 Patients Enrolled for Depression
National Institute on Aging (NIA)NIH
1,675 Previous Clinical Trials
28,020,893 Total Patients Enrolled
36 Trials studying Depression
28,321 Patients Enrolled for Depression

Media Library

DAPPER (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04091347 — N/A
Depression Research Study Groups: Wait List Control Arm, Intervention Arm
Depression Clinical Trial 2023: DAPPER Highlights & Side Effects. Trial Name: NCT04091347 — N/A
DAPPER (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04091347 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the ultimate purpose of this clinical experiment?

"This clinical trial will be monitored over the baseline, 12 week and 24 week marks to assess changes in depressive symptoms as per PROMIS 57. Additionally, secondary objectives include assessing any alterations of frailty via Frail Scale (scores ranging from 0-17), physical function through Lawton's Instrumental Activities of Daily Living (IADL) with scores range from 0-8; plus Katz Activity of Daily Living (ADL) which has a score range from 0-6 with 6 indicating full functionality and 2 or below suggesting severe impairment."

Answered by AI

Are there currently opportunities available for individuals to join this investigation?

"Unfortunately, according to clinicaltrials.gov, this trial is not taking on any more participants at the current time. The study was initially posted on 2nd January 2020 and last updated 9th November 2022. Despite that however, there are over 1800 other trials actively seeking volunteers right now."

Answered by AI

Who else is applying?

What state do they live in?
Maryland
How old are they?
65+
What site did they apply to?
Johns Hopkins School of Nursing
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
3+

Why did patients apply to this trial?

How responsive is this trial?

Most responsive sites:
  1. Johns Hopkins School of Nursing: < 48 hours
Average response time
  • < 2 Days
Typically responds via
Phone Call
Recent research and studies
clinicaltrials.govStudy
Depression and Pain Perseverance Through Empowered Recovery Intervention
2020. "Depression and Pain Perseverance Through Empowered Recovery Intervention". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04091347.
All > Depression Baltimore > Pain
~6 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top