Study Summary
This trial is investigating whether the orexin neurotransmitter system is linked to sleep disturbance and stress in opioid use disorder patients who are early in their recovery and on medication assisted treatment.
- Opioid Use Disorder
- Sleep Disorder
Treatment Effectiveness
Effectiveness Progress
Study Objectives
3 Primary · 0 Secondary · Reporting Duration: 21 days (collected over a seven-day period in weeks 1, 4, and 8 of the trial)
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Suvorexant
1 of 2
Placebo
1 of 2
Active Control
Non-Treatment Group
200 Total Participants · 2 Treatment Groups
Primary Treatment: Suvorexant · Has Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 21 - 65 · All Participants · 8 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Maryland | 100.0% |
What site did they apply to?
| Man Alive Inc., Lane Treatment Center | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
How responsive is this trial?
Average response time
- < 2 Days
Typically responds via
| Phone Call | 100.0% |
Most responsive sites:
- Man Alive Inc., Lane Treatment Center: < 48 hours
Frequently Asked Questions
Am I eligible to partake in this experiment?
"This clinical trial is in search of 200 individuals between the ages 21 to 65 who have been diagnosed with opioid use disorder. In order for participants to be accepted, they must meet these eligibility criteria." - Anonymous Online Contributor
Is Suvorexant a risk-free medication for users?
"There is preliminary data that suggests the safety of Suvorexant, therefore this medication received a score of 2." - Anonymous Online Contributor
What is the maximum capacity of people who can participate in this experiment?
"Affirmative, clinicaltrials.gov has evidence that this clinical experiment is actively seeking volunteers. It was initially posted on November 20th 2020 and recently updated on May 16th 2022. This trial requires 200 individuals to participate from 5 different sites." - Anonymous Online Contributor
Is this research available to people under thirty years of age?
"The eligibility criteria for this clinical trial dictates that participants should be between 21 to 65 years of age. Separately, there are 121 studies involving patients below the legal voting age and 504 studies which involve seniors above 65." - Anonymous Online Contributor
Are there any vacancies that participants can fill in this clinical investigation?
"According to the data available on clinicaltrials.gov, this trial is presently recruiting participants; it was first posted in November 2020 and has been recently updated as of May 16th 2022." - Anonymous Online Contributor
Is there a precedent of Suvorexant being tested in clinical settings?
"Currently, 14 clinical trials are being conducted for Suvorexant with two in their final Phase 3. While the primary research hub is located in Silver Spring, Maryland, 71 other sites have been enlisted to run these studies." - Anonymous Online Contributor