Action observation for Stroke

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Georgia Tech, Atlanta, AR
Stroke
Action observation - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

Action Observation as a Rehabilitation Intervention for Stroke

See full description

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Action observation will improve 2 primary outcomes in patients with Stroke. Measurement will happen over the course of Arm and hand movement recorded in one day during the 3 blocks of physical performance of the SRTT.

Arm and hand movement recorded in one day during the 3 blocks of physical performance of the SRTT
Arm and hand movement with the Serial Reaction Time Test (SRTT)
Eye gaze recorded in one day during the 3 blocks of video watching (action observation)
Eye gaze pattern

Trial Safety

Trial Design

1 Treatment Group

Action observation
1 of 1
Experimental Treatment

This trial requires 20 total participants across 1 different treatment group

This trial involves a single treatment. Action Observation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Action observation
Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Action observation
2020
N/A
~210

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: eye gaze recorded in one day during the 3 blocks of video watching (action observation)
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly eye gaze recorded in one day during the 3 blocks of video watching (action observation) for reporting.

Who is running the study

Principal Investigator
V. T. R.
Prof. Veronica Thessing Rowe, Assistant Professor
Georgia State University

Closest Location

Georgia Tech - Atlanta, AR

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
stroke experienced at 18 years of age or older
not undergoing any physical rehabilitation during the time enrolled in this study
mild to moderate impairments in the more affected arm and hand (i.e., movement and coordination scores on the Fugl-Meyer Assessment between 20 and 55)
no cognitive impairments (mini-mental state examination ≥ 24/30)
normal or corrected vision (National Institutes of Health Stroke Scale = 0)

Patient Q&A Section

Can stroke be cured?

"Unfortunately, there is no cure for stroke currently available. However, advances in management will likely lead to a reduction in cerebral infarction and improved outcome for many patients." - Anonymous Online Contributor

Unverified Answer

What are common treatments for stroke?

"Treatment of stroke varies by country. Both oral and intravenous medication is commonly prescribed. There is no evidence that a particular type of treatment is better in terms of effectiveness or other considerations (e.g. cost, tolerability, ease of use). There can be some controversy regarding the use of surgery when it is indicated. There is no high-quality evidence to support any specific treatment." - Anonymous Online Contributor

Unverified Answer

What are the signs of stroke?

"Many of the signs of stroke depend on each case on its own. But a few common signs can be identified that can help providers differentiate between the common causes of symptoms and more serious conditions.\n" - Anonymous Online Contributor

Unverified Answer

What is stroke?

"Strokes are categorized based largely on whether the loss of functions may be permanent or temporary. These distinctions provide a useful way to communicate between patients, caregivers, clinicians, and payers." - Anonymous Online Contributor

Unverified Answer

How many people get stroke a year in the United States?

"About 25.6 million Americans will experience a mild to disabling stroke by 2030. This number may increase to more than 30 million Americans by 2050 due to strokes that are only mild to disabling. Of all individuals with mild strokes, 13% end up having a disabling stroke. A significant portion of those with mild stroke who develop disabling strokes do so after age 40. Stroke occurs in the elderly more often and causes them to die. Strokes that occur in the brain also become more severe with age. In fact, 15% of stroke-related deaths occur among 65-to–84-year-olds." - Anonymous Online Contributor

Unverified Answer

What causes stroke?

"The cause of stroke is a combination of several conditions, which may influence the risk of stroke onset. These factors include genetics, environment, disease and lifestyle changes. These may be modified through appropriate treatments." - Anonymous Online Contributor

Unverified Answer

Is action observation typically used in combination with any other treatments?

"Adding AO training does not reduce fatigue or anxiety during rehabilitative therapy for hemiparetic stroke patients. It actually increases fatigue when combined with the use of paretic hand training. AO training is not a relevant tool when considering motor recovery after a stroke." - Anonymous Online Contributor

Unverified Answer

What is action observation?

"Based on the results and literature, action observation seems to be beneficial for treatment effectiveness. Furthermore, this method has been proven to have a significant positive effect on reducing positive and negative symptoms in clients with schizophrenia. Furthermore, no studies suggest that such treatments affect negative symptoms." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for stroke?

"It can be concluded that the current guidelines concerning the decision for a clinical trial appear to be insufficient at guiding the decision to or against performing a clinical trial. Further guidelines including advice on how to use the guideline should be developed, as well as an improved information provision for patients and professionals are urgently needed." - Anonymous Online Contributor

Unverified Answer

How does action observation work?

"The present results indicate that a significant amount of visual input is needed for observation to be effective in changing action performance or changing action behavior in healthy adults." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets stroke?

"There is a mean age when someone has their first stroke of 75 years in Finland, which is similar to an average of 71 years (in the UK). The incidence is lowest in those aged 10-19 and greatest in those over 90 years. Men experience their first stroke earlier than women (68 years versus 67 years), but the differences between men and women diminish throughout life. The age at which a stroke is diagnosed also varies as a function of the age of the person when it occurs." - Anonymous Online Contributor

Unverified Answer

Does stroke run in families?

"The frequency of the strokes was different in the families: the frequency was increased in the families with strokes as opposed to those without strokes (p = 0.04). Also the stroke survivors and their families had a different risk profile concerning the CVD risk factors except lipid profile. Data from a recent study should be confirmed by other studies, and more knowledge of the genes can lead to a better understanding of the pathogenesis." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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