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Acoustic stimuli (Startle) for Spinal Cord Injury

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Spinal Cord InjuryAcoustic stimuli (Startle) - Behavioral
Eligibility
18 - 75
All Sexes
What conditions do you have?
Select

Study Summary

This trial will help researchers understand how the body changes neurologically after a Spinal Cord Injury, which will in turn help patients with SCIs learn to live with their injury.

Eligible Conditions
  • Spinal Cord Injury

Treatment Effectiveness

Effectiveness Progress

1 of 3

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Study Objectives

10 Primary · 0 Secondary · Reporting Duration: 3-4 hours

3-4 hours
10-meter walk test
Graded and Redefined Assessment of Strength, Sensibility and Prehension (GRASSP).
Ipsilateral MEPs (iMEPs)
MEP recruitment curves
Modified Ashworth Scale (MAS)
Muscle Spasticity
Pendulum Test
Portable Spasticity Assessment Device (PSAD)'
StartReact
Toronto Rehabilitation Institute-Hand Function Test (TRI-HFT)

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
MyoPro robot only
1
Glyburide treatment arm
2
SL-1002

Trial Design

2 Treatment Groups

Aim 1
1 of 2
Aim 2
1 of 2

Experimental Treatment

120 Total Participants · 2 Treatment Groups

Primary Treatment: Acoustic stimuli (Startle) · No Placebo Group · N/A

Aim 1
Behavioral
Experimental Group · 1 Intervention: Acoustic stimuli (Startle) · Intervention Types: Behavioral
Aim 2
Behavioral
Experimental Group · 1 Intervention: Acoustic stimuli (Startle) · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3-4 hours

Who is running the clinical trial?

Shirley Ryan AbilityLabLead Sponsor
173 Previous Clinical Trials
13,582 Total Patients Enrolled

Eligibility Criteria

Age 18 - 75 · All Participants · 10 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
may result Incomplete spinal cord injuries at T12 or above may result in permanent paralysis from the waist down.
-Low cervical lesions -Cannot walk Individuals who have a low cervical lesion and who cannot walk are the inclusion criteria for spastic individuals with SCI.
You are able to voluntarily flex and extend the elbow and/or knee or ankle.
Males and females are both human beings
References

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