← Back to Search

High-fat meal with Beetroot Drink for Healthy Eating

N/A

Recruiting

Led By Philip Millar, PhD

Research Sponsored by University of Guelph

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

18-30 years of age

Healthy, free of known cardiovascular, metabolic, or musculoskeletal disease

Timeline

Screening 3 weeks

Treatment Varies

Follow Up blood collected before intervention and 1, 2, 3 hours post-intervention. blood frozen at -80 degrees celsius and analyzed at later date

Awards & highlights

Study Summary

This trial aims to understand the effects of a high-fat meal on the body's ability to reduce stress during exercise. It will also investigate whether the addition of dietary nitrate can prevent these effects. Participants

Who is the study for?

This trial is for healthy individuals aged 18-30 without cardiovascular, metabolic, or musculoskeletal diseases. Participants must not be on chronic medications (except oral contraceptives) and should avoid drugs, caffeine, alcohol, intense exercise, mouthwash, and multivitamins before the study.Check my eligibility

What is being tested?

The study investigates how a single high-fat meal affects the body's ability to regulate blood flow during exercise compared to a low-fat meal or a high-fat meal with dietary nitrate. It involves three visits where participants eat different meals and undergo handgrip exercises while being monitored.See study design

What are the potential side effects?

Since this trial involves common foods and non-invasive testing procedures like Doppler ultrasound during exercise, significant side effects are not expected. However, some may experience discomfort from the handgrip exercises or mild gastrointestinal upset from the meals.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 30 years old.

Select...

I am healthy with no known heart, metabolic, or bone/muscle diseases.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ blood collected before intervention and 1, 2, 3 hours post-intervention. blood frozen at -80 degrees celsius and analyzed at later date

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~blood collected before intervention and 1, 2, 3 hours post-intervention. blood frozen at -80 degrees celsius and analyzed at later date

This trial's timeline: 3 weeks for screening, Varies for treatment, and blood collected before intervention and 1, 2, 3 hours post-intervention. blood frozen at -80 degrees celsius and analyzed at later date for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Forearm blood flow

Forearm vascular conductance

Systolic and Diastolic Blood Pressure

Secondary outcome measures

Blood Glucose concentrations

Plasma levels of Nitrate/Nitrite concentration

Plasma levels of Norepinephrine

+1 more

Trial Design

3Treatment groups

Active Control

Placebo Group

Group I: High-fat meal with Beetroot DrinkActive Control1 Intervention

2 sausage egg McMuffins and a hashbrown from McDonalds and 10g of beetroot powder mixed in 250 mL cold tap water drink

Group II: High-fat meal with Placebo DrinkPlacebo Group1 Intervention

2 sausage egg McMuffins and a hashbrown from McDonalds and Mio water flavouring in 250 mL cold tap water. Trace amounts of sugar and sodium were mixed to match the beetroot supplement

Group III: Low-fat meal controlPlacebo Group1 Intervention

Kelloggs cornflakes (110g), greek yogurt (400g), skim milk (500 mL), and orange juice (250 mL). Energy-matched to the high-fat meal

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of GuelphLead Sponsor

80 Previous Clinical Trials

9,961 Total Patients Enrolled

Philip Millar, PhDPrincipal InvestigatorUniversity of Guelph

2 Previous Clinical Trials

47 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current number of individuals participating in this clinical research study?

"Indeed, as per the information available on clinicaltrials.gov, this ongoing trial is actively seeking participants. The trial was initially posted on January 8th, 2024 and last updated on December 15th, 2023. The study aims to recruit a total of 15 patients from one designated site."

Answered by AI

Which individuals are eligible to participate in this research study?

"To be eligible for enrollment in this experimental study, potential participants must exhibit a balanced nutritional intake and fall within the age range of 18 to 30 years. Approximately 15 individuals will have the opportunity to participate in this research project."

Answered by AI

Are there any available positions for participants in this research study?

"Indeed, the details provided on clinicaltrials.gov affirm that this particular clinical trial is currently in the active recruitment phase. The study was first published for public access on January 8th, 2024, and underwent its most recent update on December 15th, 2023. To complete the trial successfully, a total of 15 participants will be enrolled at a single site."

Answered by AI

What is the primary goal of this medical study?

"The primary objective of this clinical trial is to assess forearm blood flow. This will be evaluated at various time points, including before the intervention and 1, 2, and 3 hours after the intervention. Secondary outcomes include monitoring blood glucose levels using a blood glucose monitor, measuring triglyceride levels using a triglyceride assay kit, and quantifying norepinephrine levels through an ELISA kit."

Answered by AI

Is the clinical trial open to participants who are below the age of 75?

"To be considered for participation in this research study, individuals must meet the age requirements of being at least 18 years old but no older than 30."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effects of a High-fat Meal on Exercise-mediated Sympatholysis

Philip Millar 2024. "Effects of a High-fat Meal on Exercise-mediated Sympatholysis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06186050.