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High-fat test meal for Healthy Eating (HFM Trial)

N/A
Recruiting
Led By Kirsten E Bell, PhD
Research Sponsored by Kirsten Bell
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up will be measured in blood samples taken at 0 minutes (fasting), and 15, 30, 45, 60, 90, 120, 150, 180, 210, and 240 minutes post-ingestion of a high-fat meal
Awards & highlights

HFM Trial Summary

This trial will test whether there are differences in the way men and women metabolize high-fat meals.

HFM Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~will be measured in blood samples taken at 0 minutes (fasting), and 15, 30, 45, 60, 90, 120, 150, 180, 210, and 240 minutes post-ingestion of a high-fat meal
This trial's timeline: 3 weeks for screening, Varies for treatment, and will be measured in blood samples taken at 0 minutes (fasting), and 15, 30, 45, 60, 90, 120, 150, 180, 210, and 240 minutes post-ingestion of a high-fat meal for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Plasma c-peptide
Plasma glucagon
Plasma glucose
+1 more
Secondary outcome measures
Plasma cholesterols (total and HDL)
Plasma non-esterified fatty acids
Plasma triglycerides
+1 more

HFM Trial Design

1Treatment groups
Experimental Treatment
Group I: High-fat test mealExperimental Treatment1 Intervention
All participants will consume a high-fat breakfast after an overnight fast. This meal will consist of a flour tortilla, eggs, bacon, cheddar cheese, mayonnaise, and hashbrowns. After the initial blood sample (0 min) is drawn during Visit 2, we will ask participants to consume this breakfast within 10 minutes. This meal has been designed to mimic the amount of energy (calories) and fat contained in a typical fast-food breakfast (e.g., from Tim Hortons or McDonalds). Each meal will provide 846 kcal, derived from 54 g fat (58% energy), 61 g carbohydrate (29% energy), and 29 g protein (13% energy).

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Who is running the clinical trial?

Kirsten BellLead Sponsor
McMaster UniversityOTHER
880 Previous Clinical Trials
2,597,804 Total Patients Enrolled
Kirsten E Bell, PhDPrincipal InvestigatorMcMaster University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I meet the criteria to participate in this research endeavor?

"This clinical trial will admit 24 participants, aged 18-35 and currently following a nutritious diet. Other eligibility criteria include: A BMI between 18.5 to 30 kg/m2, Blood glucose levels of <6 mM while fasting, Blood pressure readings at or below 140/90 mmHg when resting, Weight stability within the last 6 months (± 2kg), Exercise habits that fall in line with Canadian Physical Activity Guidelinesa and no use of hormone altering contraceptives such as pills, injections etc."

Answered by AI

Is there still room to join this research initiative?

"Clinicaltrials.gov confirms that recruitment for this study is ongoing; the first listing was posted on August 22nd 2022 and edited a day later."

Answered by AI

How many participants are contributing to the clinical trial?

"Absolutely. Information from clinicaltrials.gov attests that this trial is presently recruiting participants, with the original post having been made on August 22nd 2022 and subsequently updated on August 23rd of the same year. 24 individuals are needed to be enrolled at a single site."

Answered by AI

Does the study encompass participants of any age, including those under thirty?

"This clinical trial is intended for individuals between the ages of 18 and 35. Those younger than 18, as well as those older than 65, can access two distinct studies tailored to their age groups."

Answered by AI

What are the main desired outcomes of this research endeavor?

"This medical trial intends to measure the effects of a high-fat meal on plasma insulin. Furthermore, they will be gauging Respiratory Exchange Ratio (RER), Plasma Nonesterified Fatty Acids (PEAK postprandial concentration and/or AUC) as well as Triglycerides' PEAK postprandial concentration and/or AUC over 0 minutes (fasting) and 15, 30, 45, 60, 90 120 150 180 210 240 minute interval after ingestion."

Answered by AI
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~9 spots leftby Apr 2025