Turmeric for Arthritis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial investigates whether turmeric can reduce pain and stiffness in individuals with basal joint arthritis, a type of arthritis affecting the thumb. Participants will receive either turmeric or a placebo pill three times a day for six weeks to evaluate turmeric's effectiveness. The trial suits those experiencing basal joint pain and tenderness, diagnosed with a specific stage of this arthritis through X-rays, and not currently pursuing other treatments like surgery or injections. As an unphased trial, it offers participants the chance to contribute to understanding potential new treatments for arthritis.
Is there any evidence suggesting that turmeric is likely to be safe for humans?
Research shows that turmeric is generally safe for people with arthritis. Studies have found that curcumin, a key component of turmeric, is well-tolerated by patients. These studies also found that turmeric helped reduce swelling and pain. Participants taking turmeric experienced fewer side effects compared to those who did not. Overall, turmeric appears to be an effective and safe option for managing arthritis symptoms.12345
Why are researchers excited about this trial?
Unlike standard arthritis treatments like NSAIDs or corticosteroids, which primarily focus on reducing inflammation and pain, turmeric offers a natural alternative with its active ingredient, curcumin. Curcumin is known for its anti-inflammatory and antioxidant properties, potentially reducing joint pain and swelling without the side effects commonly associated with conventional medications. Researchers are excited about turmeric because it represents a more holistic approach to managing arthritis symptoms, appealing to those seeking plant-based and less invasive treatment options.
What evidence suggests that turmeric might be an effective treatment for arthritis?
Research shows that turmeric, particularly its main ingredient curcumin, can help reduce arthritis symptoms. Studies have found that curcumin lowers inflammation and pain in people with arthritis. In some cases, turmeric extract works as well as common pain relievers like NSAIDs (non-steroidal anti-inflammatory drugs) but with fewer side effects. In this trial, participants in the turmeric group will receive a turmeric (100 mg pastille) three times per day for six weeks. Specifically, curcumin significantly reduced pain compared to a placebo, which participants in the control group will receive. Overall, turmeric appears to be a promising natural option for managing arthritis pain and stiffness.23678
Who Is on the Research Team?
Neal Chen, MD
Principal Investigator
Massachusetts General Hospital
Are You a Good Fit for This Trial?
This trial is for individuals over 40 with basal joint arthritis who experience pain and stiffness in the thumb. They must have specific symptoms, speak English, and show early-stage arthritis on X-rays. Excluded are those with other inflammatory conditions, taking certain medications like blood thinners or steroids, diabetics, pregnant women, or those pursuing other treatments.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either turmeric or placebo 3 times per day for 6 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Placebo
- Turmeric
Find a Clinic Near You
Who Is Running the Clinical Trial?
Massachusetts General Hospital
Lead Sponsor