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Implant

Cartiva Implant for Osteoarthritis(GRIP 2 Trial)

N/A
Waitlist Available
Led By Christopher Bainbridge, MB ChB, FRCSEd, CCST
Research Sponsored by Cartiva, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Preoperative VAS Pain score of ≥ 40 in the treated hand
Eaton classification stage II or III OA of the first CMC joint based on X-rays taken within 6 months of the Operative date and evidence of first CMC joint OA based on subjective review of associated clinical symptoms
Must not have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up1 year
Awards & highlights
No Placebo-Only Group

GRIP 2 Trial Summary

This trial will compare the effectiveness of Cartiva to LRTI for treating osteoarthritis of the first CMC joint in the hand.

GRIP 2 Trial Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
Select...
Your QuickDASH score, which measures your ability to perform daily tasks, is 20 or higher before surgery.
Select...
Your bones are strong enough and you don't need extra support from a bone graft.

GRIP 2 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Function measured by QuickDASH
Key Subsequent Secondary Surgical Interventions (SSSIs)
Pain measured by the Visual Analog Scale (VAS) scale
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

GRIP 2 Trial Design

1Treatment groups
Experimental Treatment
Group I: CartivaExperimental Treatment1 Intervention
Synthetic Cartilage Implant
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cartiva
2009
Completed Phase 3
~430

Find a Location

Who is running the clinical trial?

Cartiva, Inc.Lead Sponsor
6 Previous Clinical Trials
493 Total Patients Enrolled
4 Trials studying Osteoarthritis
438 Patients Enrolled for Osteoarthritis
Christopher Bainbridge, MB ChB, FRCSEd, CCSTPrincipal InvestigatorRoyal Derby Hospital
Scott Wolfe, MDPrincipal InvestigatorHospital for Special Surgery, New York

Media Library

Cartiva Implant (Implant) Clinical Trial Eligibility Overview. Trial Name: NCT03247439 — N/A
Osteoarthritis Research Study Groups: Cartiva
Osteoarthritis Clinical Trial 2023: Cartiva Implant Highlights & Side Effects. Trial Name: NCT03247439 — N/A
Cartiva Implant (Implant) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03247439 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many venues are currently offering this research endeavor?

"Presently, the trial is being hosted at 5 separate sites. These are situated in San Diego, Indianapolis and New York City with 2 additional spots scattered elsewhere. It's recommended that participants select a location near them to diminish travel burdens if they choose to join the study."

Answered by AI

Is this medical research in need of additional participants?

"Unfortunately, the data hosted on clinicaltrials.gov indicates that this medical study is not currently recruiting patients - it was initially posted in December 2017 and updated last in December 2020. However, 613 other studies are actively searching for participants at present time."

Answered by AI

Who else is applying?

What state do they live in?
Georgia
New York
How old are they?
65+
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
0
2
What site did they apply to?
Hospital for Specialty Surgery

Why did patients apply to this trial?

I have had steroid injections with limited relief. Hand PT with some relief.
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)
2017. "Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03247439.
All > Osteoarthritis > Oa
~11 spots leftby Nov 2024
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