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Cell Therapy

Micro-Fragmented Adipose Tissue (MFAT) for Arthritis

Phase 2

Waitlist Available

Led By Jacques Hacquebord, MD

Research Sponsored by NYU Langone Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, month 12

Awards & highlights

Study Summary

This trial is testing whether or not injecting processed fat into the thumb CMC joint can help with arthritis. 32 patients with stage 2-3 CMC arthritis will be randomly chosen to receive either the treatment or a corticosteroid injection. The trial will exclude patients with inflammatory arthritis or prior thumb base trauma or surgery. The fat will be harvested from the outer thigh or lower abdomen using local anesthesia, then processed and injected into the thumb CMC joint under fluoroscopic guidance. VAS, grip/pinch strength, Kapandji range of motion score, thumb disability examination, and QuickDASH score will be assessed pre-procedure and

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, month 12

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, month 12

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, month 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percent Change in Score on Pain Visual Analog Scale (VAS)

Secondary outcome measures

Change in Kapandji Range of Motion Score

Change in Score on Thumb Disability Exam (TDX)

Change in Shortened Disabilities of the Arm, Shoulder, and Hand (QuickDASH) Score

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: MFATExperimental Treatment1 Intervention

Group II: Steroid (Control)Active Control1 Intervention

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Who is running the clinical trial?

NYU Langone HealthLead Sponsor

1,366 Previous Clinical Trials

839,661 Total Patients Enrolled

13 Trials studying Arthritis

1,729 Patients Enrolled for Arthritis

Jacques Hacquebord, MDPrincipal InvestigatorNYU Langone Health

1 Previous Clinical Trials

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the scope of the current patient cohort for this clinical trial?

"Affirmative. As per clinicaltrials.gov, this healthcare investigation is recruiting individuals and was first published on the 12th of May 2022 with its most recent update taking place July 1st 2022. The study needs to enlist 32 participants from a single site."

Answered by AI

What deleterious effects might Micro-Fragmented Adipose Tissue (MFAT) pose to patients?

"Because the clinical trial is in Phase 2, our team at Power believes that Micro-Fragmented Adipose Tissue (MFAT) has a safety rating of two. This means there is evidence to support its safety but not efficacy yet."

Answered by AI

Have any other studies employed Micro-Fragmented Adipose Tissue (MFAT) as a therapeutic option?

"Currently, there are 41 separate clinical trials being conducted for Micro-Fragmented Adipose Tissue (MFAT). Of those studies, 8 have progressed into Phase 3. The majority of the MFAT research is taking place in Columbia, Missouri; however, 75 sites across the nation are also running their own experiments on this potential therapy."

Answered by AI

Is this experiment still recruiting participants?

"Affirmed, this trial is recruiting. It was initially announced on May 12th 2022 and subsequently revised July 1st of the same year as per clinicaltrials.gov's records."

Answered by AI

What medical ailments can Micro-Fragmented Adipose Tissue (MFAT) address?

"Micro-Fragmented Adipose Tissue (MFAT) is used to combat ulcerative colitis, disorders of the hand, and neurodegenerative diseases located in the brain."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Autologous Intra-Articular Micro-Fragmented Adipose Transfer for the Treatment of Thumb Carpometacarpal Joint Arthritis

2022. "Autologous Intra-Articular Micro-Fragmented Adipose Transfer for the Treatment of Thumb Carpometacarpal Joint Arthritis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05005000.