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Corticosteroid

Drug lower dose for Anesthesia

N/A
Waitlist Available
Led By Barry D Kussman, MBBCh
Research Sponsored by Boston Children's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during surgical procedure
Awards & highlights

Study Summary

This study is evaluating whether a new technology can help measure brain activity in response to pain.

Eligible Conditions
  • Anesthesia
  • Pain

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during surgical procedure
This trial's timeline: 3 weeks for screening, Varies for treatment, and during surgical procedure for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Utilization of NIRS to measure changes in oxyhemoglobin and deoxyhemoglobin in the somatosensory and prefrontal cortices in response to noxious stimulation, and whether these changes are reduced or eliminated by remifentanil.

Trial Design

3Treatment groups
Active Control
Placebo Group
Group I: Drug lower doseActive Control1 Intervention
Remifentanil infusion
Group II: Drug higher doseActive Control1 Intervention
Remifentanil infusion
Group III: PlaceboPlacebo Group1 Intervention
Normal saline infusion

Find a Location

Who is running the clinical trial?

Boston Children's HospitalLead Sponsor
763 Previous Clinical Trials
5,580,575 Total Patients Enrolled
Barry D Kussman, MBBChPrincipal InvestigatorBoston Children's Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Assessing the Cortical Response to Noxious and Auditory Stimuli Using Near Infrared Spectroscopy in Subjects Under General Anesthesia
Barry Kussman 2016. "Assessing the Cortical Response to Noxious and Auditory Stimuli Using Near Infrared Spectroscopy in Subjects Under General Anesthesia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02703090.
All > Anesthesia
~6 spots leftby May 2025
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