Low Intensity Focused Ultrasound for Parkinson's Disease

Phase-Based Progress Estimates
University of California, Los Angeles, Los Angeles, CAParkinson's DiseaseActive LIFUP Treatment - Device
18 - 65
All Sexes
What conditions do you have?

Study Summary

This trial will test a new, non-invasive therapy that could improve Parkinson's Disease symptoms. It could be the first step towards a medication-free treatment.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

4 Primary · 2 Secondary · Reporting Duration: Change from Baseline at 2 weeks

Week 2
Motor Assessment 2: 9-Hole Pegboard Dexterity Test
Week 2
Motor Assessment 1: Finger Tapping
Week 2
Motor Assessment 3: Unified Parkinson Disease Rating Scale (UPDRS)
Week 2
BOLD fMRI Signal in Putamen
MRI Task: Implicit Learning Paradigm
Perfusion ASL fMRI Signal throughout Brain

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Low Intensity Focused Ultrasound
1 of 2
1 of 2

Experimental Treatment

Non-Treatment Group

30 Total Participants · 2 Treatment Groups

Primary Treatment: Low Intensity Focused Ultrasound · Has Placebo Group · N/A

Low Intensity Focused Ultrasound
Experimental Group · 1 Intervention: Active LIFUP Treatment · Intervention Types: Device
ShamComparator Group · 1 Intervention: Sham LIFUP Treatment · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: change from baseline at 2 weeks

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,420 Previous Clinical Trials
6,748,816 Total Patients Enrolled
Taylor P Kuhn, Ph.D.Principal InvestigatorUniversity of California, Los Angeles

Eligibility Criteria

Age 18 - 65 · All Participants · 0 Total Inclusion Criteria

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Frequently Asked Questions

Are individuals being accepted into this research study at present?

"Checking the clinicaltrials.gov listing, it appears that this study is still recruiting participants; posted on June 15th 2022 and last modified March 13th 2023." - Anonymous Online Contributor

Unverified Answer

Is eligibility for this experiment limited to those over 18 years of age?

"According to the requirements outlined in the trial protocols, individuals must be of legal age (minimum 18) and under 65 years old to participate." - Anonymous Online Contributor

Unverified Answer

Who is qualified to participate in this experiment?

"This clinical trial seeks 30 participants with a Parkinson's Disease diagnosis and of age 18-65. Eligibility criteria is strictly limited to those conditions." - Anonymous Online Contributor

Unverified Answer

How many volunteers have signed up for the trial thus far?

"Affirmative. Per the information published on clinicaltrials.gov, this investigation is actively seeking subjects for participation. It was posted to the website on June 15th 2022 and last updated March 13th 2023; 30 participants are needed from a single site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.