BX Pulsar 1002 (LIFUP) Low intensity Focused Ultrasound Pulsation for Chronic Disease
This study is evaluating whether low intensity focused ultrasound can help people with disorders of consciousness.
See full descriptionAbout the trial for Chronic Disease
Treatment Groups
This trial involves 2 different treatments. BX Pulsar 1002 (LIFUP) Low Intensity Focused Ultrasound Pulsation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether BX Pulsar 1002 (LIFUP) Low intensity Focused Ultrasound Pulsation will improve 4 primary outcomes in patients with Chronic Disease. Measurement will happen over the course of This will be conducted on Day 4..
Who is running the study
Principal InvestigatorPatient Q & A Section
What causes chronic disease?
Chronic diseases are caused by a combination of many factors. They are not just individual diseases. Factors may include social structure, health behaviour and environmental factors, rather than single gene defects, for example in chronic diseases such as diabetes.
What are the signs of chronic disease?
Individuals will demonstrate signs and symptoms by their chronologic stage. They can be as early as 30 years of age and as late as 85 years of age.
What are common treatments for chronic disease?
Chronic diseases are more than just an economic burden: they have a substantial impact upon daily life. Many treatments have been researched, and more still are needed to be developed. One of the challenges of chronic disease research is development of standardized outcome measures. The scope of the problem is enormous (it covers all diseases), and the development of standardized patient-reported outcome measures would be a first step in providing an evidence base for patient-centered treatment choices.
How many people get chronic disease a year in the United States?
The USPSTF recommends that men and women ages 50 to 74 years receive routine screening for colorectal cancer, breast cancer, and prostate cancer. Screening is especially valuable for men before the age of 70 years because prostate cancer screening has a relatively low sensitivity and many men will be unnecessarily diagnosed and treated with inappropriate surveillance strategies.
What is chronic disease?
Chronic disease and comorbidities make up a large percentage of the health care system's resource use. They make up more than one-third of a patient's visits to primary care clinics or hospitals in the United States and contribute to roughly half of total spending on these visits. Although the term comorbidity is used very widely, there are many other approaches to define chronic disease. Given the wide range of disease and outcomes described in the literature, standardized terminology is needed to allow comparisons of data to be made between studies and across time and settings.
Can chronic disease be cured?
There are several misconceptions, but the most common are that chronic disease can hardly be cured and that most chronic diseases are chronic only because the body's immune system fails to attack these problems as in immunosenescence, or fails to recover from these damages. Chronic disease can be cured with the same methods as acute disease like an infection or fever. However, it is important to know when chronic disease has actually been cured. At the opposite extreme, it is the body that may be cured by a physician that wants to be cured. Chronic disease and chronic illness are two sides of the same coin.
What is the primary cause of chronic disease?
Primary chronic diseases are a cause of concern to the individual. Individuals are at serious risk if they are unable to recognize their own chronic disease risks or if their primary disease has progressed to a more advanced stage. It may be difficult for primary care physicians to perform a full assessment of primary disease risk. Individuals with secondary causes of chronic disease are the best candidates for secondary prevention, for example with proper nutrition and adequate exercise.
Is bx pulsar 1002 (lifup) low intensity focused ultrasound pulsation typically used in combination with any other treatments?
The combination of LIFUP with non-invasive and non-palliative conservative treatment was seen as of minimal efficacy. The combination of LIFUP with chemotherapy was not effective against liver or pancreatic cancer. The use of LIFUP as a salvage therapy in these cases is likely to be ineffective.
What is bx pulsar 1002 (lifup) low intensity focused ultrasound pulsation?
Recent findings suggest that BxP1002 LIFU is a promising adjunct to standard of care modalities such as IM guided catheters and IM guided catheter localization for local ablation of prostate adenoma tissue(https://www.ncbi.nlm.nih.gov/pubmed/!searchTerm?term= prostate cancer+localization+guid+guide)?.
Who should consider clinical trials for chronic disease?
There is insufficient evidence in the literature to support the assertion that clinical trial participation in chronic disease can lead to benefit for people with that disease.
Has bx pulsar 1002 (lifup) low intensity focused ultrasound pulsation proven to be more effective than a placebo?
Bx pulsar 1002 has demonstrated superiority to a placebo for the treatment of chronic low back pain, but this may be because the efficacy of lupa is related to the placebo effect.
What is the average age someone gets chronic disease?
Age at diagnosis of the chronic disease correlates strongly and linearly with most chronic disease prevalence rates. The average age of the population at a given chronic disease prevalence is generally the same across many chronic diseases. [Fig.