Colchicine for Osteoarthritis of the Knee(CLOAK Trial)

"The cut-off age for this clinical trial is 99 years, with all participants being of legal adult age or older."

"As indicated on clinicaltrials.gov, the trial is presently recruiting participants and was first published in May 2019 with its most recent update occurring November 2022."

"At this time, 31 clinical trials are researching the use of Colchicine 0.8 mg or 0.6 mg orally in daily intervals with 12 Phase 3 studies underway. Although many of these investigations occur around New York City, there exist a total of 98 sites where they can be found worldwide."

"Colchicine 0.8 mg or 0.6 mg taken orally once a day is rated 3 due to its Phase 4 status, which indicates it has been approved for public use."

"Colchicine, a medication administered orally at 0.8 or 0.6 mg per day, is the most frequented treatment for gout flares and other ailments including familial mediterranean fever, postcommissurotomy syndrome, and behcet's syndrome."

"Indeed, the data hosted on clinicaltrials.gov indicates that this medical experiment is actively seeking participants since it was put online in May 15th 2019 and last updated on November 3rd 2022. As of now, a total of 120 individuals are required for trial at one single site."

"This medical trial is recruiting 120 patients with arthrosis ranging from 18 to 99 years old. In order to apply, the patient must have a BMI of 32 or lower at enrollment, consent to be randomized between colchicine and placebo for three months, and be 40 years or older."