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Colchicine for Atrial Fibrillation (COP-AF Trial)
COP-AF Trial Summary
This trial will assess whether the administration of oral colchicine will reduce the incidence of perioperative atrial fibrillation in patients undergoing major thoracic surgery.
- Atrial Fibrillation
- Atrial Flutter
- Myocardial Injury
COP-AF Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2021 Phase 4 trial • 280 Patients • NCT01709981COP-AF Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Are there a lot of medical facilities conducting this clinical trial in Canada?
"This trial is being conducted by the Institut universitaire de cardiologie et de pneumologie de Québec, the CIUSSS de l'Estrie - CHUS, and St. Joseph's Healthcare Hamilton as well as 17 other research facilities."
What are some of the known risks associated with Colchicine?
"Colchicine efficacy has been supported by some data, while there have been multiple reports affirming its safety. Consequently, our team has given it a score of 3."
How many people are currently enlisted in this trial?
"That is accurate. The information available on clinicaltrials.gov suggests that this study is still seeking participants. This clinical trial was first posted on February 14th, 2018 and was last edited on November 3rd, 2022. They are recruiting for 3200 participants across 17 locations."
For what purpose is Colchicine most commonly prescribed?
"gout flares are often best managed through Colchicine medication. However, Colchicine can also be taken to help with conditions such as behcet's syndrome, postcommissurotomy syndrome, and familial mediterranean fever."
What is the general scientific consensus on Colchicine's efficacy?
"Dr. Hamid Ahmadieh first studied colchicine in 2006. Since that time, 18,334 clinical trials have been completed with colchicine. As of now, there are 32 active trials involving colchicine, a majority of which are located in Québec, Quebec."
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