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Anti-metabolites

Capecitabine for Pancreatic Cancer

Phase 2

Waitlist Available

Led By Theodore S Hong, MD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 years

Awards & highlights

Study Summary

This trial is testing a different type of radiation therapy (proton beam) in combination with two different chemotherapy drugs (capecitabine and hydroxychloroquine) to see if it is more effective in treating pancreatic cancer than the standard photon radiation and capecitabine treatment.

Eligible Conditions

Pancreatic Cancer

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Progression-free survival

Secondary outcome measures

Biomarkers

Describe QoL

Local control

+7 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: HydroxychloroquineExperimental Treatment3 Interventions

Hydroxychloroquine with chemoradiation

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Capecitabine

FDA approved

Hydroxychloroquine

FDA approved

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor

2,934 Previous Clinical Trials

13,198,531 Total Patients Enrolled

Theodore S Hong, MDPrincipal InvestigatorMassachusetts General Hospital

6 Previous Clinical Trials

139 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do you know of any other research that has been conducted using Capecitabine?

"As of now, 419 separate studies are being conducted on capecitabine. 137 of those trials are currently ongoing and in their third stage. Most research locations for this medication are situated in Woolloongabba, Queensland; however, there are a total of 13847 sites running clinical trials worldwide."

Answered by AI

How many individuals are currently taking part in this research project?

"Unfortunately, this study is no longer recruiting patients. The trial was first posted on December 1st 2011 and last updated February 1st 2021. At the moment, there are 726 other trials searching for participants with malignant neoplasm of pancreas and 419 studies for Capecitabine actively looking for participants."

Answered by AI

Are there any current openings for participants in this clinical trial?

"According to the latest update on clinicaltrials.gov, this particular study is not looking for more participants at this time. This trial was first posted on December 1st, 2011 and updated February 1st, 2021. Although this study isn't enrolling patients right now, there are 1145 other studies that are actively recruiting."

Answered by AI

Has the government given its okay to market capecitabine?

"Capecitabine has not been proven effective yet, but there is some evidence that it is safe, so it received a score of 2."

Answered by AI

What is the most common reason that doctors prescribe Capecitabine?

"While capecitabine is most commonly used to treat q fever, it has also been found to be effective in the treatment of malaria, sjögren's syndrome, and metastatic colorectal carcinoma."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Short Course Radiation Therapy With Proton or Photon Beam Capecitabine and Hydroxychloroquine for Resectable Pancreatic Cancer

Theodore Sunki Hong 2011. "Short Course Radiation Therapy With Proton or Photon Beam Capecitabine and Hydroxychloroquine for Resectable Pancreatic Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01494155.