Asthma Clinical Trials 2022

Asthma studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect asthma clinical trial in 2022.

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This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.

Phone-Based Intervention

The primary purpose of this pragmatic randomized clinical trial is to examine whether the addition of a phone-based multicomponent environmental intervention customized for Houston public housing residents with asthma will result in statistically significant improvements in key measures of…

This study is an efficacy-implementation trial to: evaluate systematically the efficacy of BREATHE in 200 Black adults receiving care at urban federally qualified health centers (FQHCs) for uncontrolled asthma; and identify multi-level barriers and facilitators to the widespread adoption …

To asses effectiveness and safety of tezepelumab in adult and adolescent participants with severe asthma including several under-studied populations in the United States.

Budesonide 80 μg and Formoterol Fumarate Dihydrate 4.5 μg

The purpose of the study is to demonstrate the Pharmacodynamic bioequivalence of the test product to the reference product in adult patient with Asthma

Methacholine Chloride

Pharmacodynamic bioequivalence study of Albuterol Sulfate Inhalation Aerosol 0.09 mg

The primary objective of this study is to evaluate the efficacy of AVTX-002 compared with placebo in patients with poorly controlled non-eosinophilic asthma (NEA).

Smoking is the main cause of preventable disease and death in the US and impacts respiratory illnesses including COPD and asthma. However, little is known about the effects on smoking and lung health of substituting cigarettes with ENDS in adults with asthma. This project aims to test whet…

Service men and women returning from deployment are significantly more likely to develop asthma and severe respiratory symptoms from airway obstruction. Why this happens is not well known, but exposure to diesel, burn pits, biomass smoke, and sandstorms are thought to play a role. Ultimate…

This study examines the implications of providing hospital-level care in rural homes.

Semaglutide Pen Injector 2.4mg weekly

This is a randomized placebo-controlled trial of semaglutide, an FDA-approved therapy for the treatment of type 2 diabetes mellitus and obesity, in adults with symptomatic asthma despite the use of inhaled steroids and with excess body weight. This study will test the central hypothesis th…

This is a randomised, placebo-controlled, double-blind study with an active comparator (montelukast) arm to assess the efficacy and safety of AZD5718 administered at multiple dose levels over a 12-week treatment period to adult participants with moderate-to-severe uncontrolled asthma.

This is a 24 week study to evaluate the efficacy and safety of budesonide and formoterol fumarate metered dose inhaler in adults and adolescents with inadequately controlled asthma.

vDOT Intervention Group

This study is evaluating whether video directly observed therapy is more effective than standard asthma care.

Combined coping skills + asthma management

Uncontrolled asthma in school-aged children is a significant public health problem. Latino children living in low-income contexts are at increased risk for uncontrolled asthma compared to non-Latino white children, and stress is an unaddressed factor in this disparity. Therefore, the purpo…

This is a first in human (FIH) clinical study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD8630 in healthy adults (Part A) and adult asthma patients on medium to high dose inhaled corticosteroids / Long-acting beta-agonists (Part B)

This study is evaluating whether increasing doses of Amitriptyline and Duloxetine can reduce cough frequency in patients with refractory chronic cough.

This study is evaluating whether repeated exposures to ozone can help people with asthma and exercise-induced bronchoconstriction adapt to exercise.

This is a parallel, treatment, Phase 2, double-blind, 2 arm, 12-week Proof of Concept (PoC) study that is designed to assess the efficacy, safety, and tolerability of rilzabrutinib in adult participants (aged 18-70 years) with moderate-to-severe asthma who are not well controlled on inhale…

This is an interventional, randomized, parallel group, treatment, Phase 3b/4, double blind, 2-arm study to assess the effect of dupilumab compared to standard of care therapy on preventing or slowing the rate of lung function decline in adult patients with uncontrolled moderate to severe a…

Controlling Asthma Program for Adolescents (CAMP Air)

This study is evaluating whether an e-health program can help control asthma in adolescents.

This study is evaluating whether salbutamol inhaler use can improve lung function and reduce inflammation in people with asthma and/or EIB exercising in ozone air pollution.

This study is evaluating whether a drug called tezepelumab can improve the immune response to a flu vaccine.

This study is evaluating whether dupilumab can improve lung function and quality of life in people with severe asthma.

Interferon gamma-primed mesenchymal stromal cells (MSCs)

This study is evaluating whether allogeneic bone marrow derived MSCs are safe and tolerable in children.

Social Media Enhanced Education

This study is evaluating whether social media enhanced education will reduce healthcare utilization and costs.

ASTHMAXcel ED Application

This study is evaluating whether a prototype ASTHMAXcelED app can be used in the emergency department.

This study is evaluating whether dupilumab is more effective than omalizumab in reducing polyp size and improving sense of smell.

This study is evaluating whether inhaler use can be used to predict asthma exacerbations and response to biologics.

Telehealth Education for Asthma Connecting Hospital and Home

This study is evaluating whether a set of activities can improve asthma control in children.

This study is evaluating whether a long-acting muscarinic antagonist might be a safe and effective treatment for children with nonatopic mild persistent asthma.

This study is evaluating whether a drug called nabilone can help people with asthma.

Electronic Asthma Shared Decision-Making App

This study is evaluating whether an electronic Shared Decision Making application is feasible and acceptable for patients with asthma.

This study is evaluating whether a drug called CCSJ117 can be used safely and effectively to treat asthma.

This study is evaluating whether a school-based asthma program is feasible for children with poorly controlled asthma.

Improving Asthma Care Together (IMPACT)

This study is evaluating whether a set of activities can improve asthma control in children with asthma.

Digihaler Albuterol Device by TEVA

This study is evaluating whether an electronic adherence monitoring albuterol rescue inhaler can improve proper use in a mostly minority and inner-city population of children treated for asthma at the Children's Hospital of Los Angeles.

Interactive Video (IAV) Telemedicine

This study is evaluating whether a new technology can help improve asthma symptoms.

The primary objective of this community program intervention study is to assess the process and potential benefits of integrating the AIRQ™, Asthma Checklist, and educational resources (PRECISION program) into clinical practice using either in-person or telehealth visits. The secondary ob…

This study is evaluating whether a drug may help improve asthma symptoms for individuals with an eosinophilic phenotype.

This study is evaluating whether a medication which is known to help with allergy symptoms may help reduce symptoms of Meniere's Disease.

Community Health Navigator Program

This study is evaluating whether a patient navigation program can improve care for patients with multiple long-term health conditions.

Community Health Navigator Program

This study is evaluating whether a patient navigation program can improve care for patients with long-term health conditions.

Community Health Navigator Program

This study is evaluating whether a patient navigation program can improve care for patients with long-term health conditions.

This study is evaluating whether a drug called CBP-201 may help treat asthma.

Cough is the most common presenting symptom to family physician. Chronic Cough affects approximately 10-12% of the general population and is one of the commonest reasons for referral to secondary care. Unfortunately, there are no licensed treatments for this debilitating condition, which i…

Mobile Monitoring Device

Recently, interest in ways to monitor and care for patients remotely has significantly increased due to concerns for infection control as well as a way to increase access to regular clinic visits that may be limited for socioeconomic and geographic reasons. However, remote care can be limi…

GSK3511294 (Depemokimab)

This study is evaluating whether a drug may help treat asthma.

GSK3511294 (Depemokimab)

This study is evaluating whether switching participants who have benefitted from mepolizumab or benralizumab to GSK3511294 is non-inferior to maintaining current

GSK3511294 (Depemokimab)

This study is evaluating whether a drug may help improve asthma symptoms for individuals who have not responded to standard treatments.

This study is evaluating whether a breathing machine may help reduce asthma symptoms in children.

Short acting beta agonist (SABA) (rescue medication)

This is a randomised, placebo-controlled, double-blinded, multi-centre, 2-part study to assess the efficacy and safety of inhaled AZD1402. Part 1 will be performed in a Lead-in Cohort for each dose level to evaluate the safety and pharmacokinetics (PK) in a population with asthma controlle…

This study is evaluating whether a mobile phone app can help improve adherence to asthma medication for children in rural South Carolina.

This study is evaluating whether a new type of MRI can help doctors better assess lung function.

Segmental allergen challenge

This study is evaluating whether a specific type of white blood cell may be associated with asthma.

BGF MDI 320/28.8/9.6 μg

This study is evaluating whether a new combination of medications may help treat severe asthma.

BGF MDI 320/28.8/9.6 μg

This study is evaluating whether a new combination of medications may help treat severe asthma.

Digital Tools for Asthma Self-Management

This study is evaluating whether digital tools can improve asthma control.

This study is evaluating whether a school-based intervention can help reduce asthma symptoms for urban schoolchildren.

Study D9181C00001 is a Phase II, randomised, double-blind, placebo-controlled, parallel group, proof of concept study to evaluate the efficacy, safety, pharmacokinetics (PK) and immunogenicity of MEDI3506 in adult participants with uncontrolled moderate to severe asthma on standard of care…

Cognitive Processing Therapy

This study is evaluating whether a novel intervention may help improve outcomes for individuals with asthma and post-traumatic stress disorder.

Hyperpolarized 129XeMRI

This study is evaluating whether a new imaging technique can help identify the causes of asthma in obese individuals.

Primary Objective: To assess the effect of dupilumab on sleep Secondary Objectives: To evaluate the effect of dupilumab on additional patient reported sleep outcomes To evaluate the effect of dupilumab on objective sleep assessment To evaluate the effect of dupilumab on asthma symptoms …

This study is evaluating whether a new treatment for asthma may be effective.

This study is evaluating whether a drug may help improve lung function in patients with asthma.

This study is evaluating whether a mobile health app can help improve asthma symptoms and healthcare utilization.

Primary Objective: o To assess the effect of dupilumab on lung function and related changes in airway volumes detectable by functional respiratory imaging Secondary Objective: To evaluate the effect of dupilumab at Week 24 on bronchodynamics, hyperinflation, airway resistance, airway wa…

This study is evaluating whether a new intervention may help improve adherence to asthma medications for adolescents.

This study is evaluating whether a drug may help treat asthma in children.

Medication monitoring

This study is evaluating whether an electronic medication monitor can help adolescents take their asthma medications.

The primary objective of the study is to demonstrate that dupilumab treatment improves exercise capacity in patients with moderate-to-severe asthma. The secondary objectives of the study are: To demonstrate that dupilumab treatment increases physical activity of daily living in patients …

This study is evaluating whether a specific breathing technique may help reduce the frequency of asthma attacks in obese children.

Daily oral vitamin D3, 3,333 IU

This study aims to answer the question whether daily oral vitamin D supplementation can reduce the risk of respiratory or lung complications in children and adolescents with sickle cell disease. Respiratory problems are the leading causes of sickness and of death in sickle cell disease. Th…

This study is evaluating whether an arts-based health education program can improve health and well-being.

This study is evaluating whether a number of different treatments for asthma may be effective.

This study is evaluating whether roflumilast may help improve asthma symptoms for individuals with low T2.

This study is evaluating whether a drug called MTPS9579A might help people with asthma.

This study is evaluating whether a new model of care can help improve asthma management for teens.

Easy Breathing program

This study is evaluating whether a program which teaches asthma management to healthcare providers may improve asthma outcomes in rural youth.

Asthma-related deaths are more numerous among low-income minority patients and older adults with chronic diseases. Guidelines for asthma management have not addressed the needs of these groups. The investigators recently demonstrated the feasibility, acceptability, and evidence of effectiv…

Triamcinolone Acetonide

This study is evaluating whether a steroid injection may help reduce asthma symptoms.

RhDNAse Inhalation Solution

This study is evaluating whether a new treatment for asthma may be effective.

Medication Therapy Management (MTM) Video Telehealthcare

This study is evaluating whether a new approach to asthma management may help improve asthma control.

The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics. Changes will be assessed over 48 week treatment period in patients with persistent symptoms despite standard therapy of inhaled corticosteroids (ICS) p…

PiCASO Intervention Group

This study is evaluating whether a peer support coaching intervention may help improve self-management for adolescents and young adults with childhood onset chronic conditions.

This study is evaluating whether an app can help improve the quality of life for individuals with autism spectrum disorder.

Asthma is caused by or worsened by different things in different people. It is because of these differences that not all people with asthma respond the same to all treatments and medicines. If the investigators can better identify the changes in the airways or breathing pipes in patients w…

This study is evaluating whether a program of care coordination can improve asthma outcomes in children.

Daily Adherence Reminders/Adherence Performance Feedback

This study is evaluating whether financial incentives can help improve adherence to inhaled corticosteroids for children with asthma.

This study is evaluating whether a steroid medication is more effective than another in treating children with asthma.