CBOT + TAU for Opioid Use Disorder (CBOT-OUD Trial)

"This study is looking for 190 people with cravings aged 18 to 70. The most important criteria for applicants are as follows: being willing to receive study interventions and buprenorphine during the study, not meeting criteria for current moderate or severe use of other substance abuse disorders (except nicotine), age 18-70 years, diagnosis of current moderate or severe OUD in the past 6 months including the past one month, diagnosis of Major Depressive Disorder, Anxiety disorders, and Post-traumatic Stress Disorder included as long as symptoms are stable with no suicidal ideation or plans and no recent changes in treatment within the last 6 weeks prior"

"That is correct. The clinicaltrials.gov website lists this trial as recruiting, with the original posting on March 26th, 2021 and the most recent update being July 30th, 2021. There are 4 locations for this study looking to enroll a total of 190 participants."

"The age range for participants in this study is 18 to 70 years old."

"There is some evidence backing up CBOT + TAU's safety, but not its efficacy. Consequently, it received a score of 2."

"The primary goal for this study, which will be assessed over a 6-month period, is to observe negative affect severity in the PANAS. Additionally, researchers will monitor changes in opioid craving and withdrawal symptoms as well as relapse rates."

"The information available on clinicaltrials.gov verifies that this experiment is still actively recruiting patients. This research project was originally published on March 26th, 2021 and was most recently updated on July 30th, 2021. In total, the study needs 190 individuals from 4 different locations."