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Ibuprofen for Toothache

Phase 3
Waitlist Available
Research Sponsored by Walter Reed National Military Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 48 hours
Awards & highlights

Study Summary

This trial will compare the effects of two different oral premedications on the efficacy of a nerve block for patients with symptomatic irreversible pulpitis.

Eligible Conditions
  • Toothache

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~48 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 48 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Analgesic Effect on Nerve Block
Secondary outcome measures
Analgesic Effect on Post-Operative Pain
Analgesic Effect on Supplemental Anesthesia Techniques

Trial Design

2Treatment groups
Experimental Treatment
Group I: 800mg IbuprofenExperimental Treatment1 Intervention
Subject will take 800mg of Ibuprofen 45 minutes prior to anesthetic delivery.
Group II: 40mg MethylprednisoloneExperimental Treatment1 Intervention
Subject will take 40mg of Methylprednisolone 45 minutes prior to anesthetic delivery.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Methylprednisolone
FDA approved
Ibuprofen
FDA approved

Find a Location

Who is running the clinical trial?

Walter Reed National Military Medical CenterLead Sponsor
137 Previous Clinical Trials
34,494 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis
John Neal 2020. "Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04157036.
~1 spots leftby Apr 2025
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