300 Participants Needed

Calcium Fructoborate for Joint Discomfort

JL
Overseen ByJennifer L Robinson, Ph.D.

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a natural supplement called calcium fructoborate (CFB) to see if it can reduce joint pain in adults. The supplement may help by reducing inflammation in the body. Participants will take the supplement daily for a few months to measure changes in their joint discomfort and overall well-being. Calcium fructoborate (CFB) is a dietary supplement used for managing joint discomfort, leveraging the benefits of organic boron-containing molecules.

Are You a Good Fit for This Trial?

This trial is for people aged 40-65 with knee osteoarthritis and chronic knee pain, who haven't taken antibiotics or joint discomfort drugs recently. Participants need basic computer skills, a smartphone, and reliable internet to join the virtual study but can't have certain health conditions like cardiovascular diseases or diabetes.

Inclusion Criteria

I have had knee pain for more than 3 months.
You should have basic computer skills.
I haven't taken NSAIDs or pain relievers for 2 weeks and can avoid them during the study.
See 9 more

Exclusion Criteria

I have an ongoing infection or inflammation.
I have been prescribed medication for joint pain or osteoarthritis in the last 3 months.
I have diabetes or another metabolic disorder.
See 12 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either 216mg CFB or placebo daily for 90 days. Check-in questionnaires are administered on days 1, 5, 14, 21, 28, 60, and 90.

12 weeks
7 virtual check-ins

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Calcium Fructoborate
  • Placebo
Trial Overview The study tests if Calcium Fructoborate (CFB), a dietary supplement, can relieve joint discomfort over 90 days compared to a placebo. Participants will be randomly assigned to take either CFB or an inactive substance daily in this virtually conducted trial.
How Is the Trial Designed?
2Treatment groups
Active Control
Placebo Group
Group I: Calcium FructoborateActive Control1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Auburn University

Lead Sponsor

Trials
81
Recruited
14,600+
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