Your session is about to expire
← Back to Search
ABP-450 for Migraine Prevention
Study Summary
This trial will study if ABP-450 could help prevent migraines in adults who get six or more migraine days per month. The study will have 690 patients from the US, Canada, and Australia.
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2022 Phase 2 trial • 61 Patients • NCT04849988Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I have had COVID-19 which worsened my migraines, am not pregnant or planning to be during the study, and am not related to or employed by the study team.Women who can become pregnant must have a negative urine pregnancy test at their first visit.If I have a fever or COVID-19 symptoms, I must get tested and treated by my doctor.If you are a woman of childbearing age, you must agree to use a reliable form of birth control throughout the entire study.You are willing and able to adhere to the study assessments, visit schedules, and prohibitions, as described in this protocol.
- Group 1: ABP-450 - Low Dose
- Group 2: ABP-450 - High Dose
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the target enrollment for this specific clinical trial?
"Recruitment for this clinical trial has concluded. The initiation date was October 19th 2021 and the last update occurred on November 17th 2022. If you are searching for alternative studies, there are currently 172 trials that accept patients with migraine and 61 research projects where ABP-450 is being tested which are still accepting participants."
What potential risks does ABP-450 pose to those using it?
"There is some safety data available for ABP-450, so our team at Power assigned it a score of 2. This drug has yet to pass phase 3 trials, indicating the lack of efficacy results."
What conditions are typically treated with ABP-450?
"ABP-450 is the leading treatment for urinary incontinence and can also prove beneficial in addressing spinal cord issues, botox injections, as well as overactive bladder syndrome."
What objectives does this experiment intend to realize?
"This experiment, conducted over a 48-week period from baseline to the end of treatment, will primarily measure the incidence of adverse events. Secondary outcomes include evaluating anti-drug antibodies for ABP-450 and assessing changes in monthly migraine days requiring medications as well as headache hours across treatment groups."
Are there a number of health centers conducting this research trial in the city?
"To participate in this medical trial, prospective participants can find a recruiting centre such as Diex Recherche Québec in Quebec, META Medical Research Institute LLC located in Dayton or the New England Institute for Neurology and Headache situated in Stamford. Additionally, there are 48 other sites accepting enrolments now."
To what extent has ABP-450 been investigated in other research studies?
"Currently, there are 61 active clinical investigations into ABP-450 with 20 of them at the final Phase 3 stage. For the sake of convenience, most enrolment for these studies is occurring in Farmington Hills, Michigan; however, ABP-450 trials are taking place across 754 other sites around the world."
Is the enrollment phase of this research still open?
"The clinicaltrials.gov database reveals that this particular medical trial, which was first published on October 19th 2021, is not currently taking in new participants. However, 233 other studies are recruiting patients at the time of writing."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
How responsive is this trial?
Most responsive sites:
- Los Angeles Headache Center: < 24 hours
Typically responds via
Average response time
- < 1 Day
Share this study with friends
Copy Link
Messenger