This trial is evaluating whether Dehydrated alcohol will improve 1 primary outcome and 22 secondary outcomes in patients with Hypertension. Measurement will happen over the course of Procedure date (day 0).
This trial requires 300 total participants across 2 different treatment groups
This trial involves 2 different treatments. Dehydrated Alcohol is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 3 and have had some early promising results.
Some signs of hypertension include lack of effort in work, or tiredness during work. More than half of people with hypertension also report feeling dizzy or lightheaded when standing up from a seated or recumbent position.
It is difficult to determine why hypertensive individuals may not be diagnosed and treated, but some risk factors are known. These may include those outlined below. Many of these risk factors are modifiable by lifestyle changes, physical activity, and weight loss. However, it is also important to make sure that lifestyle changes do not worsen the problem, and to make sure that people with hypertension are treated successfully and thoroughly.
Hypertension is defined as high blood pressure that is consistently well controlled at home or work. In the U.S. approximately 1.6 billion adults have high blood pressure. Hypertension is the leading risk factor for cardiovascular disease. Hypertension is strongly defined by race and ethnicity.
Only a minority of people with hypertension need medication. Most treatments involve lifestyle changes, and medications can be more effective if used at the early stages of hypertension.
More males have hypertension than females. The prevalence estimates among various ethnicities are comparable to estimates on the prevalence of hypertension in the population in the United States. There are clear links between hypertension and coronary diseases in all ethnic groups with the exception of the Asians.
A single-drug treatment of diuretics and calcium channel blockers combined with lifestyle intervention reduces systolic blood pressures significantly more than a placebo or only low-pressure dietary regimen. The therapeutic effect of blood pressure reduction does not worsen diabetes-related complications of hypertension.
Alcoholic beverages have some beneficial effects when used in combination with other treatments. On the other hand, alcohol is associated with adverse effects when used in combination with benzodiazepines as well as other treatments.
The use of low-potency alcohol (> 20% alcohol by volume) prior to surgery may have a similar adverse influence on postoperative health as a high-potency agent in an anaesthetic.
Data from a recent study was conducted in a convenience sample. The impact of alcohol consumption on quality of life for patients with hypertension warrants further study.
The prevalence and mortality of hypertension has fallen between 1986 and 2006. Prevention and treatment of hypertension will require an integrated approach but will be a challenging task.
The authors found that no patient has a higher QALY than a clinician. Only when the QALYs of patients exceed those of clinicians are the patients considered "cost-effective" to treatment with antihypertensive medications. Clinical trials involving patients have important implications for treatment guidelines and payers because it may affect the cost-benefit ratio of antihypertensive therapy in terms of the number of patient lives saved versus patient-related quality of life and drug prices.
Overall the incidence of HT is low, but most of the cases occur for the elderly. The age group with highest incidence is people 40-year-old and over. More female than male people are diagnosed with HT.