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Forced Desynchrony for High Blood Pressure

N/A

Recruiting

Led By Steven A Shea, PhD

Research Sponsored by Oregon Health and Science University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Free of all prescription and non-prescription drugs (including caffeine, nicotine, alcohol and herbal medications)

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 7-day lab stay

Awards & highlights

Study Summary

This trial will help determine if different therapies for hypertension are effective for black adults based on the root cause of their hypertension.

Who is the study for?

This trial is for self-identified Black or White adults who are either 'normotensive' with blood pressure under 140/90 mmHg, or have stage 1 hypertension with systolic BP between 140 and 160 mmHg or diastolic BP between 90 and 100 mmHg. Participants should not be on any medication (including caffeine and alcohol), must not smoke, do night shifts, or have traveled across time zones recently. They also shouldn't have severe health issues like renal disease.Check my eligibility

What is being tested?

The study investigates how sleep, circadian rhythms, and behaviors contribute to non-dipping blood pressure profiles in Black adults compared to White adults. It aims to understand if race influences the best treatment for hypertension by examining these different factors.See study design

What are the potential side effects?

Since this trial involves behavioral interventions rather than medications, there may be minimal side effects related directly to the intervention itself. However, changes in sleep patterns could potentially cause temporary fatigue or stress.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am not taking any prescription, over-the-counter drugs, or substances like caffeine or alcohol.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 7-day lab stay

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~7-day lab stay

This trial's timeline: 3 weeks for screening, Varies for treatment, and 7-day lab stay for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Blood pressure

Heart rate variability

Secondary outcome measures

24-hr ambulatory blood pressure

beat-by-beat blood pressure

flow mediated dilation

+6 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Forced DesynchronyExperimental Treatment1 Intervention

All participants will undergo a forced desynchrony protocol.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Forced Desynchrony

2014

N/A

~40

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor

973 Previous Clinical Trials

7,385,760 Total Patients Enrolled

6 Trials studying Cardiovascular Risk

1,630 Patients Enrolled for Cardiovascular Risk

Steven A Shea, PhDPrincipal InvestigatorOre

3 Previous Clinical Trials

73 Total Patients Enrolled

1 Trials studying Cardiovascular Risk

16 Patients Enrolled for Cardiovascular Risk

Media Library

Forced Desynchrony Clinical Trial Eligibility Overview. Trial Name: NCT03558893 — N/A

Cardiovascular Risk Research Study Groups: Forced Desynchrony

Cardiovascular Risk Clinical Trial 2023: Forced Desynchrony Highlights & Side Effects. Trial Name: NCT03558893 — N/A

Forced Desynchrony 2023 Treatment Timeline for Medical Study. Trial Name: NCT03558893 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are being included in this clinical trial?

"Affirmative. At the time of writing, clinicaltrials.gov outlines that this research is actively enrolling participants. The study was originally posted on December 1st 2018 and recently updated on May 27th 2022 for a total of 52 patients to be recruited from one trial site."

Answered by AI

What key goals is this medical study aiming to achieve?

"This clinical trial, which will be conducted over a 7-day period in the laboratory, seeks to examine Heart Rate Variability. Additional outcomes include Flow Mediated Dilation as an indicator of endothelial function, Venous Aldosterone for assessing renin-angiotensin and sympathetic nerve activation, and Beat-by-Beat Blood Pressure that is monitored non-invansively using a device on the fingers."

Answered by AI

Does this clinical experiment currently have open enrollment?

"Confirmed. Clinicaltrials.gov's information indicates that this investigation is presently recruiting sufferers, with the first posting taking place on December 1st 2018 and a subsequent update on May 27th 2022. 52 individuals need to be enrolled across one medical center for data collection purposes."

Answered by AI

Could I be a potential candidate for this research study?

"To be granted access to this medical trial, participants must have hypertension and a chronological age ranged between 40 and 60. A maximum of 52 people will be admitted into the study."

Answered by AI

Could individuals aged 35+ enroll in this research program?

"The participation requirements for this medical trial involve individuals aged 40 to 60. Those younger than 18 are eligible for 57 other studies while 723 trials await those over 65."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Health Disparities in Prevalence of Hypertension Between Black and White Americans

Steven A. Shea 2018. "Health Disparities in Prevalence of Hypertension Between Black and White Americans". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03558893.

All > Hypertension