This trial is evaluating whether Renal Denervation will improve 2 primary outcomes and 5 secondary outcomes in patients with Cardiovascular Diseases. Measurement will happen over the course of From baseline to 2 months post procedure.
This trial requires 300 total participants across 1 different treatment group
This trial involves a single treatment. Renal Denervation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"The main risk factors for cardiovascular disease are: the size of the heart; elevated blood pressure; high levels of blood sugar and low levels of blood cholesterol. People living in warmer climates are at an elevated risk of heart disease due to the effect of climate on their blood sugar levels, and elevated levels of blood cholesterol. Smoking, alcohol, dietary fat and sugar and the presence of atherosclerosis, can also result in heart disease.\n" - Anonymous Online Contributor
"The prevalence of vascular disease is increasing (especially among older persons), as is the magnitude of that increase. As a part of an overall population-based approach, screening for vascular disease should be emphasized. Physicians should play a role in the prevention of cardiovascular disease." - Anonymous Online Contributor
"A total of 11,000 deaths occur every day – of which approximately half are due to cardiovascular diseases. Chronic and debilitating diseases, like cancer, Alzheimer's disease and cardiovascular disease, cause considerable suffering and social and economic losses." - Anonymous Online Contributor
"Cardiovascular signs include palpitations, shortness of breath, palpitations, chest pain, palpitations, heart palpitations, abnormal heart rhythms or palpitations, shortness of breath, lightheadedness or syncope and swelling to the legs, ankles or feet." - Anonymous Online Contributor
"Antiacids and the long-term use of aspirin and other anti-inflammatory drugs may be useful in the prevention of cardiovascular diseases. For patients with heart attack or stroke, folic acid, a drug approved by the Food and Drug Advisory Committee of the Food and Drug Administration (FDA), is widely recommended for consumers. Oral statins (atorvirate, lipitor, etc.) may improve outcome. Statins have also been studied as a therapy for cancer prevention, with mixed results. Statins are contraindicated in patients with an acute coronary syndrome or the need for cardiothoracic surgery, among other things." - Anonymous Online Contributor
"In some cases, it is possible to eradicate cardiovascular disease, but it is more efficient to prevent it, and to promote a healthy lifestyle. A balanced diet and regular physical exercise are the best choices to maintain proper cardiovascular health, as they have negative effects on cardiovascular disease as well as being affordable and easily accessible." - Anonymous Online Contributor
"The role of RDN for the treatment of HF is expanding. There was a significant paucity of information regarding use in combination with CABG or pacemaking." - Anonymous Online Contributor
"RDA is an effective and safe surgical procedure that can reduce many of the physiological and pathological symptoms of heart failure. It has also been proven to improve the survival rate of patients who suffer from heart failure and is used as salvage or alternative therapy for patients who have other treatments that cannot control symptoms or reverse the underlying cause of their condition. However, there are some adverse effects that can occur after this surgery including bleeding and an increased risk of developing an atrial fibrillation. These risks can be minimized if patients are given proper post-operative care. Patients should return regularly to the hospital to perform cardiac assessments, so as to ensure that their condition is adequately managed. If any problem appear during the procedure, then one must take it seriously." - Anonymous Online Contributor
"Current research in renal denervation uses different techniques. While some authors suggest that denervation is efficient in certain circumstances, others report conflicting results for these same circumstances. Current results indicate that a clear evidence based on large multicenter studies, randomized controlled trials, in line with the currently established indications, is the only acceptable way of proving the efficiency." - Anonymous Online Contributor
"Recent advancements in cardiovascular science have led to better patient care in the treatment of a number of cardiovascular conditions. There are many treatment options for the management of [congestive heart failure] (CHF), and as cardiovascular conditions become more and more manageable, better quality of life continues to improve. There are specific therapies that have been shown to improve patient outcomes. [Recently, the use of cardiac stem cells (CSCs) has also been shown to increase cardioprotection, improve remodeling, and reduce LV systolic function after [myocardial infarction"" - Anonymous Online Contributor
"Data from a recent study suggest that the safety margin for renal denervation for cardiovascular disease risk reduction is very narrow. Thus, clinical practice should consider the magnitude of the desired effect and risk-outcomes balance in particular patients before renal denervation for managing hypertension." - Anonymous Online Contributor
"Until now, the main treatments only target coronary vasoconstriction; however, our study suggests that there is scope for investigating other complementary therapeutic approaches to treat hypertension as well as prevention of atherosclerosis, the main cause of cardiovascular disease." - Anonymous Online Contributor