MitoQ for High Blood Pressure

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
High Blood Pressure+3 MoreMitoQ - DietarySupplement
Eligibility
19 - 75
All Sexes
What conditions do you have?
Select

Study Summary

This trial will help explain why black individuals are at increased cardiovascular disease risk and if mitochondrial reactive oxygen species play a role in this.

Eligible Conditions
  • High Blood Pressure
  • Racial Disparities
  • Kidney Function
  • Cardiovascular Risk

Treatment Effectiveness

Study Objectives

6 Primary · 7 Secondary · Reporting Duration: Before and one hour after supplementation or placebo

Baseline (pre-intervention)
Cardiorespiratory fitness
Habitual dietary intake
Mental health - depression
Mental health - social anxiety
Objective sleep duration and quality
Physical activity
Subjective sleep duration and quality
Before and one hour after supplementation or placebo
Changes in blood biomarkers of nitric oxide bioavailability
Changes in blood pressure reactivity
Changes in circulating reactive oxygen species
Changes in flow-mediated dilation (FMD)
Changes in indices of arterial stiffness
Sympathectomy

Trial Safety

Trial Design

2 Treatment Groups

MitoQ
1 of 2
Placebo
1 of 2

Experimental Treatment

Non-Treatment Group

60 Total Participants · 2 Treatment Groups

Primary Treatment: MitoQ · Has Placebo Group · N/A

MitoQ
DietarySupplement
Experimental Group · 1 Intervention: MitoQ · Intervention Types: DietarySupplement
Placebo
DietarySupplement
PlaceboComparator Group · 1 Intervention: MitoQ · Intervention Types: DietarySupplement
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MitoQ
2006
Completed Phase 2
~220

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: before and one hour after supplementation or placebo

Who is running the clinical trial?

Auburn UniversityLead Sponsor
52 Previous Clinical Trials
13,639 Total Patients Enrolled

Eligibility Criteria

Age 19 - 75 · All Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are between the ages of 19-75.
You are not currently smoking, using smokeless tobacco, nor smoked within the past 12 months.
You are not currently taking any prescription medications that could interfere with the safety of exercise.