Proton beam radiotherapy (PBRT) for Head and Neck Cancer

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Head and Neck CancerProton beam radiotherapy (PBRT) - Radiation
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will compare the side effects of two different types of radiation therapy for head and neck cancer.

Eligible Conditions
  • Head and Neck Cancer

Treatment Effectiveness

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 1 year

1 year
number of patients with grade 2 or greater acute mucositis

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

2 Treatment Groups

Proton beam radiotherapy (PBRT)
1 of 2
Photon intensity modulated radiation therapy (IMRT)
1 of 2

Experimental Treatment

108 Total Participants · 2 Treatment Groups

Primary Treatment: Proton beam radiotherapy (PBRT) · No Placebo Group · Phase 2

Proton beam radiotherapy (PBRT)
Radiation
Experimental Group · 1 Intervention: Proton beam radiotherapy (PBRT) · Intervention Types: Radiation
Photon intensity modulated radiation therapy (IMRT)
Radiation
Experimental Group · 1 Intervention: Photon intensity modulated radiation therapy (IMRT) · Intervention Types: Radiation

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 1 year

Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor
1,832 Previous Clinical Trials
584,430 Total Patients Enrolled
41 Trials studying Head and Neck Cancer
4,386 Patients Enrolled for Head and Neck Cancer
Mount Sinai Hospital, New YorkOTHER
33 Previous Clinical Trials
1,222,942 Total Patients Enrolled
Mayo ClinicOTHER
2,922 Previous Clinical Trials
3,517,045 Total Patients Enrolled
9 Trials studying Head and Neck Cancer
729 Patients Enrolled for Head and Neck Cancer
Nancy Lee, MDPrincipal InvestigatorMemorial Sloan Kettering Cancer Center
11 Previous Clinical Trials
1,324 Total Patients Enrolled
3 Trials studying Head and Neck Cancer
371 Patients Enrolled for Head and Neck Cancer

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
A salivary gland cancer is a cancer that develops in the salivary glands.
You are eligible for the study if you are aged greater than or equal to 18 years.
You have ipsilateral radiation.