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(18F)-FEPPA PET/MRI Imaging for Frontotemporal Dementia
Study Summary
This trial will use hybrid PET/MRI imaging to study neuroinflammation in frontotemporal dementia patients and its relationship to cerebral perfusion.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You have received a high amount of radiation from medical procedures in the past year, exceeding the allowed limit set by Health Canada.My symptoms are not due to a major neurological condition other than possible Frontotemporal Dementia.You have been diagnosed with schizophrenia according to specific criteria.You have important issues with your B12 levels or thyroid function that could affect the study.I can see and hear well enough for brain function tests.You have evidence of infection or other focal lesions on your brain MRI scans.I do not have any major illnesses that would prevent me from following the study's requirements.I do not have conditions like absent pulse, specific vessel diseases, burns, poor circulation, or infections that would prevent arterial line placement.I am willing to join a year-long imaging study.I can have an MRI and PET scan and have no health issues preventing them.I haven't taken any experimental drugs in the last month.You have had severe depression or bipolar disorder in the past year, or you have experienced psychotic features, agitation, or behavior issues in the last 3 months that could make it hard to follow the study rules.I am not pregnant, breastfeeding, and cannot become pregnant.I have been diagnosed with probable Frontotemporal Dementia or I am neurologically healthy with no history of neurological issues.I am in good health with no conditions that could affect the study.
- Group 1: (18F)-FEPPA
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the cap on enrollment for this clinical experiment?
"Correct. Based on the details presented on clinicaltrials.gov, this medical experiment is actively recruiting participants and first appeared online August 1st of 2016. Currently, 40 patients are needed from a single site for enrollment in the trial."
What types of participants is this investigation best suited for?
"To be eligible to enter this clinical trial, the patient must have been diagnosed with semantic dementia and within a certain age range (30-95 years old). The total number of participants that will be accepted is 40."
Can seniors aged sixty or over participate in this experiment?
"Meet the requirements for this medical trial? Individuals must be between 30 and 95 years old. On the other hand, there are a total of 30 studies available to those under 18 and 423 additional ones targeting people 65 or older."
Does this research program currently accept participants?
"Affirmative, the trial is presently inviting participants to take part in it. This clinical study was first uploaded on August 1st 2016 and underwent its latest revision on September 2nd 2020. Forty patients are needed at a single medical centre."
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