Compassion meditation for Moral Injury

Recruiting · 18+ · All Sexes · Bedford, MA

This study is evaluating whether compassion meditation can be delivered to a diverse group of Veterans with PTSD.

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About the trial for Moral Injury

Eligible Conditions
Post Traumatic Stress Disorder (PTSD) · Stress Disorders, Traumatic · Stress Disorders, Post-Traumatic

Treatment Groups

This trial involves 2 different treatments. Compassion Meditation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Compassion meditation
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.
Applied relaxation


This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Able/willing to consent
Veteran status
is intrusive memories or flashbacks of the traumatic event show original
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 10 weeks
Screening: ~3 weeks
Treatment: Varies
Reporting: 10 weeks
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 10 weeks.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Compassion meditation will improve 7 primary outcomes and 2 secondary outcomes in patients with Moral Injury. Measurement will happen over the course of 10 weeks.

An average of 3 items rated on a Likert scale.
Initiation rate
Proportion of subjects who initiate the intervention among all consented subjects.
Enrolment rate
Proportion of consented subjects among all screened and eligible patients.
Per protocol completion rate
Proportion of subjects who complete 6 or more sessions (out of a total of 10 sessions) of intervention among those who start the intervention.
Therapist fidelity to intervention
Percent compliance ("yes" or "no") with whether they addressed items within 3 element types (whether they addressed the elements unique and essential, essential but not unique, proscribed) and overall.
Practice time
Number of minutes of practice divided the number of minutes assigned.
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Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Have there been other clinical trials involving compassion meditation?

Compassion meditation interventions (CMIs) seem to be underutilized. However, it is difficult to conduct rigorous, large-scale, clinical trials comparing CMIs with usual care (e.g., CBT for PTSD).

Anonymous Patient Answer

What are common treatments for moral injury?

Consistent with other research on common treatments for trauma, treatments focused on the physical and psychological needs of survivors are common. These include psychotherapy, trauma workshops, and emotional support groups. Although a growing number of studies are examining common treatments for moral injury that do not include victim-survivor groups, this is the first published research to evaluate common treatments found to be used in the context of moral injury.

Anonymous Patient Answer

What are the signs of moral injury?

Moral injuring involves personal moral violations. These can manifest as a lack of interest in the well-being of others (and even personal injury to others for their needs), personal moral neglect,

Anonymous Patient Answer

How many people get moral injury a year in the United States?

[Over 75% of American physicians prescribe and endorse self-injury to treat mental pain or to maintain mood stability. This practice is recommended by the American Psychiatric Association. In a survey of US physicians, it was found that nearly half of the physicians that answered would prescribe or endorse the practice of self-harm. A survey of all US adults was also conducted, which revealed that about 15% of adults report having done self-harm in the previous 12 months.] In 2003, a national survey of US adults by Harris found, “More than three times as many adults as a year ago reported attempting suicide, had deliberately inflicted serious physical harm or made suicide attempts because of a mental illness.

Anonymous Patient Answer

What is moral injury?

Moral injury is a common and disabling mental health condition that manifests itself after a person encounters a troubling situation and perceives the person experiencing that situation as morally wrong. MBI is most commonly reported by adolescents and young adults. This article explores what is morally wrong and what constitutes moral injury.

Anonymous Patient Answer

Can moral injury be cured?

Moral injury is challenging to heal because it is a chronic and often difficult-to-treat injury. In the long-term, there was a significant decrease in the severity, but not a return to pre-injury scores and a significant decrease in perceived severity. Moral injury is therefore a chronic, potentially refractory injury. Future efforts in rehabilitation should acknowledge this fact and take it into account while developing rehabilitation techniques.

Anonymous Patient Answer

What causes moral injury?

Moral injury seems to be a more powerful and broader concept than guilt. In addition, while moral injury is associated with negative consequences for personal behavior, guilt is mainly related with personal consequences for others. The consequences are not the same in both cases. For moral injury, there are more serious consequences, including shame, for the individual concerned.

Anonymous Patient Answer

What does compassion meditation usually treat?

Compensatory responses are commonly reported to the effects of MCT, in particular for emotional distress. However, our study also showed that participants may have perceived that the MCT process had a tangible effect (as measured by their self-reported ratings of emotional distress). In a recent study, findings call for further refinement of the conceptual models underpinning the intervention, in particular the effects of meditation on the sense of being close to the deceased.

Anonymous Patient Answer

Is compassion meditation safe for people?

In a recent study, findings give preliminary support for the safety and feasibility of CM for adults with a history of PTSD. Future research should include a randomized comparison group to rule out concerns about the placebo effect.

Anonymous Patient Answer

Who should consider clinical trials for moral injury?

More doctors than nurses may consider clinical trial enrollment for moral injury. The factors that predicted enrollment included the possibility of treatment benefit, being from a low income population, or being married. Doctors are more likely to be considering clinical trial enrollment for moral injury than nurses.

Anonymous Patient Answer

What is compassion meditation?

Compassion meditation focuses on a compassionate approach to others, especially those who may suffer, or to our self in the form of personal or emotional conflicts. Results from a recent paper of this study have important implications for health care professionals.

Anonymous Patient Answer

What is the average age someone gets moral injury?

This review provides a baseline estimate of the prevalence of moral injury and identifies several age ranges that were most frequently seen in this population.

Anonymous Patient Answer
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