Ketamine for Opioid Addiction

"The primary measure of this clinical trial's efficacy over 72 hours post-dose is Post-surgical opioid utilization determined by electronic medication review. Secondary measures include a Pre-surgical emotional distress related to depression assessment using the PROMIS Emotional Distress-Depression Short Form questionnaire (scalable from 8, least severe, to 40 most severe), Pain Catastrophizing Scale (from 0 - 56) rating pre-surgery pain experienced in the past 14 days, and finally an evaluation of anxiety levels through the PROMIS Emotional Distress Anxiety Short Form questionnaire ranging from 7 - 35."

"This medical trial requires that prospective participants are aged between 18 and 70. Those younger than 18 can join 63 other studies, while those older than 65 have 649 clinical trials available to them."

"Affirmative. Clinicaltrials.gov lists this medical trial as actively searching for test subjects, with the original posting date being December 17th 2019 and the most recent edit occurring on December 3rd 2021. 20 participants need to be recruited across a single site."

"Taking all available evidence into account, our team has assigned Ketamine a rating of 2 due to the Phase 2 trial data that suggests safety but is lacking in efficacy."

"Affirmative. Clinicaltrials.gov documents show that this research initiative, which was originally launched on December 17th 2019, is actively seeking participants to join the trial. 20 individuals are required at a single location for successful completion of the study."

"This clinical trial is open to 20 volunteers in the 18-70 age range who suffer from chronic pain. Criteria for selection includes those undergoing lumbar, thoracic or cervical spine surgery of a maximum 6 levels and patients with backache that has persisted longer than three months."