AML Clinical Trials

Acute myeloid leukemia studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect aml clinical trial.

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CONDITION

Acute Myeloid Leukemia

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The purpose of this study is to evaluate the safety, tolerability, and preliminary clinical activity of CC-95251 alone and in combination with antineoplastic agents in participants with relapsed or refractory acute myeloid leukemia and relapsed or refractory and treatment-naive higher risk…

This study is evaluating whether a drug called DSP 5336 can help treat people with acute myeloid leukemia (AML).

This study is evaluating whether a drug called CC-91633 might be safe and effective for people with acute myeloid leukemia.

The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of CC-486 (ONUREG®) in combination with venetoclax in relapsed and/or refractory Acute Myeloid Leukemia (AML) and newly diagnosed AML.

This study is evaluating whether a drug called VOR33 may help treat acute myeloid leukemia.

This study is evaluating whether a drug may help treat acute myeloid leukemia.

This study is evaluating whether a type of white blood cell called natural killer cells may help treat acute myeloid leukemia.

This study is evaluating whether a drug called cusatuzumab can be safely combined with other drugs used to treat AML.

This study is evaluating whether a drug called CPX-351 may help individuals with chronic obstructive pulmonary disease.

Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior induction regimens: Experimental arm: DFP-10917 14-day continuous intravenous (IV) infusion at a dose of 6 mg/m²/day followed by a 14-day resting perio…

This study is evaluating whether a drug may help treat a type of leukemia.

Pevonedistat is a medicine to treat people with blood cancers or solid tumors. The main aim of the study is to learn about the levels of pevonedistat in the blood of participants with blood cancers or solid tumors, who also have severe kidney problems or mild to moderate liver problems. T…

This study is evaluating whether a new treatment for leukemia can be effective.

This study is evaluating whether a new drug called CPX-351 is safe and effective for treating older people with acute myeloid leukemia.

This study is evaluating whether a combination of two drugs may help treat myelodysplastic syndrome or chronic myelomonocytic leukemia.

AG-120 (ivosidenib) with Azacitidine

This study is evaluating whether a combination of two drugs may help treat a type of leukemia.

This study is evaluating whether a drug called MBG453 can be safely given to people with leukemia.

This study is evaluating whether a drug may help treat acute myeloid leukemia and high-risk myelodysplastic syndrome.

This study is evaluating whether a drug may help treat blood cancers.

This study is evaluating whether a drug called azacitidine can be used to treat people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML).

This study is evaluating whether a type of white blood cell called a T-cell may help treat acute myeloid leukemia.

This study is evaluating whether a drug called BI 836858 can be safely given with a drug called decitabine.

This phase I/2 trial studies the side effects and best dose of activated natural killer cells in treating patients with relapsed or refractory acute myeloid leukemia and myeloid dysplastic syndromes. Giving chemotherapy before a donor natural killer cell infusion helps stop the growth of c…

This study is evaluating whether a drug called azacitidine can improve survival for people with AML.

This study is evaluating whether a new treatment for acute myeloid leukemia (AML) is safe.

methotrexate/hydrocortisone/cytarabine

The purpose of this study is to test the safety and determine the best dose of venetoclax and selinexor when given with chemotherapy drugs in treating pediatric and young adult patients with acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) that has come back (rela…

This study is evaluating whether a combination of drugs may help treat acute myeloid leukemia.

This study is evaluating whether a combination of drugs may be more effective than a single drug in treating patients with acute myeloid leukemia or acute lymphoblastic leukemia.

IFN-γ (interferon gamma-1b) injection

This study is evaluating whether a type of white blood cell may help treat leukemia.

This study is evaluating whether a drug may help treat leukemia.

Liposome-encapsulated Daunorubicin-Cytarabine

This study is evaluating whether a new drug called CPX-351 works better than standard chemotherapy in treating patients with secondary acute myeloid leukemia who are younger than 60 years old.

This study is evaluating whether a drug called BMS-986165 may help treat patients with advanced solid tumors.

This study is evaluating whether a drug that is already being used to treat depression can also be used to treat cluster headaches.

This study is evaluating whether a combination of two drugs may be more effective than one drug alone in treating patients with acute myeloid leukemia or myelodysplastic syndrome.

This study is evaluating whether a combination of two drugs may be more effective than either drug alone for individuals with a certain type of leukemia.

This study is evaluating whether a combination of chemotherapy drugs and a drug that blocks enzymes may help treat acute myeloid leukemia.

This study is evaluating whether a drug called ONC201 may help improve the survival of patients with a certain type of leukemia.

This study is evaluating whether a drug may help treat acute myeloid leukemia.

Gemtuzumab Ozogamicin 2 mg/m^2

This study is evaluating whether a combination of two drugs may help treat acute myeloid leukemia.

This study is evaluating whether a drug may help treat AML.

Single Photon Emission Computed Tomography

This study is evaluating whether a virus which has been changed in a certain way, may be able to kill cancer cells without damaging normal cells.

This study is evaluating whether a combination of two drugs may help treat patients with myelodysplastic syndrome or acute myeloid leukemia.

This study is evaluating whether a combination of chemotherapy drugs and a drug that blocks the growth of cancer cells may be more effective than chemotherapy alone for treating patients with acute myeloid leukemia or high

This study is evaluating whether a drug combination can be safely given to people with AML.

This study is evaluating whether a PET/CT scan can measure response to treatment in patients with acute myeloid leukemia.

This study is evaluating whether a combination of chemotherapy drugs may help treat acute myeloid leukemia, high-risk myelodysplastic syndrome, or blastic phase chronic myeloid

This study is evaluating whether AG-120 may be effective in treating blood cancers.

This is a phase 1 study to test the safety of escalating doses of elesclomol sodium given to patients with advanced myeloid leukemia.

Specialty Palliative Care

This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).

CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory AML

This study is evaluating whether a combination of venetoclax and oblimersen can be safely given to people with relapsed or refractory hematologic malignancies.

Liposome-encapsulated Daunorubicin-Cytarabine

This study is evaluating the best dose and side effects of liposomal cytarabine, daunorubicin, and gemtuzumab ozogamicin in treating pediatric patients with acute myeloid leukemia that has returned after treatment (relapsed) or does not respond to

This study is evaluating whether a drug called lemzoparlimab is safe and effective in treating people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

This study is evaluating whether a combination of chemotherapy drugs may help treat acute myeloid leukemia.

This is a Phase 1, 2-part, open-label, multicenter, first-in-human (FIH) study to assess the safety, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of TAS1553 administered orally to participants ≥18 years of age with relapsed or refractory (R/R) acute myelo…

Behavioral: UR-GOAL communication tool

This study is evaluating whether a new communication tool may help improve communication between patients and their caregivers.

This study is evaluating whether a drug may help treat acute myeloid leukemia and myelodysplastic syndrome.

This study is evaluating whether a combination of chemotherapy and immunotherapy may help treat acute myeloid leukemia.

This study is evaluating whether a combination of chemotherapy and ivosidenib may be more effective than chemotherapy alone for treating acute myeloid leukemia.

This study is evaluating whether a combination of two drugs may help patients with acute myeloid leukemia.

This study is evaluating whether a combination of two drugs may help treat acute myeloid leukemia.

Primary Objective: To evaluate the anti-leukemic activity of isatuximab in combination with standard chemotherapies in pediatric participants of ages 28 days to less than 18 years with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Acute Myeloid Leukemia (AML) Secondary Object…

This study is evaluating whether a combination of two immunotherapy drugs may help treat patients with leukemia or myelodysplastic syndrome.

This study is evaluating whether a drug may help treat AML.

This study is evaluating whether a combination of two drugs can be safely given to people with acute myeloid leukemia.

This study is evaluating whether venetoclax works better when given with combination chemotherapy.

This study is evaluating whether a radioactive substance linked to a monoclonal antibody may help kill cancer cells and have less of an effect on healthy cells before donor stem cell transplant.

Venetoclax

Greenfield Park, Canada

Greenfield Park, Canada

18+

All Sexes

This study is evaluating whether a drug called venetoclax can improve survival in people with acute myeloid leukemia.

This study is evaluating whether a treatment plan based on how a patient responds to chemotherapy may help treat acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome

This study is evaluating whether a combination of drugs may be more effective than single drugs in treating acute myeloid leukemia.

This study is evaluating whether a drug called eltrombopag olamine can help improve the recovery of platelet counts in older patients with Acute Myeloid Leukemia (AML) undergoing induction (the first treatment given for a disease) chemotherapy.

This study is evaluating whether a drug called decitabine works better when given with or without a drug called bortezomib.

This study is evaluating whether a combination of chemotherapy and dasatinib is better than chemotherapy alone in treating patients with newly diagnosed acute myeloid leukemia.

This study is evaluating whether a new drug combination can improve survival in people with leukemia.

Educational Intervention

This study is evaluating whether a digital health coaching program may help leukemia patients report information about their health while receiving treatment, which may lead to improvement in overall health.

Decitabine and Cedazuridine

This study is evaluating the side effects of a combination of drugs in treating acute myeloid leukemia.

This study is evaluating whether a new drug may help treat acute myeloid leukemia.

Idarubicin Hydrochloride

This study is evaluating whether a combination of chemotherapy and a drug called KRT-232 may help treat acute myeloid leukemia.

This study is evaluating whether a combination of three drugs may help treat Philadelphia chromosome-positive acute myeloid leukemia or myeloid blast phase or accelerated phase chronic myelogenous leukemia.