← Back to Search

Procedure

FFRct versus SPECT for Cardiovascular Abnormalities (AFFECTS Trial)

Phase 3
Waitlist Available
Led By David Brown, MD
Research Sponsored by Baylor Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 months
Awards & highlights

AFFECTS Trial Summary

This study is evaluating whether a new test can help determine if a person has significant coronary artery disease.

AFFECTS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Positive finding of hemodynamically significant CAD according to FFRct.
Positive finding of hemodynamically significant CAD according to ICA +/- iFFR.
Positive finding of hemodynamically significant CAD according to SPECT.
Secondary outcome measures
Cumulative radiation exposure in the study cohort during SPECT, cCTA, and ICA and potential impact of FFRct in reducing radiation exposure in patients with no hemodynamically significant CAD.
Physician intuition regarding presence of vessel-specific, hemodynamically significant CAD after review of FFRct results.
Potential economic impact of FFRct in decreasing referral to ICA in patients without hemodynamically significant CAD.

AFFECTS Trial Design

1Treatment groups
Experimental Treatment
Group I: FFRct versus SPECTExperimental Treatment1 Intervention
Comparison of the diagnostic performance of FFRct and SPECT in subjects with suspected stable CAD

Find a Location

Who is running the clinical trial?

Baylor Research InstituteLead Sponsor
200 Previous Clinical Trials
202,956 Total Patients Enrolled
David Brown, MDPrincipal InvestigatorBaylor Research Institute
4 Previous Clinical Trials
489 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Heartflow (AFFECTS)
2016. "Heartflow (AFFECTS)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02973126.
~31 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top